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Cavaliers vs. Clippers prediction: Cleveland to win, Donovan Mitchell projected for big game in Wednesday's NBA matchup [2/4/2026]

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Written by Jason Bevilacqua

Get Cleveland Cavaliers vs Los Angeles Clippers predictions for NBA Wednesday.

Cleveland Cavaliers-Los Angeles Clippers Predictions and Game Preview.
Cleveland Cavaliers vs. Los Angeles Clippers NBA prediction for Wednesday, February 4, 2026.

NBA action continues on Wednesday at 10:30 PM ET as the Cleveland Cavaliers square off with the Los Angeles Clippers at Intuit Dome.

Based on the latest simulation results and today’s injury news, Dimers' advanced NBA model predicts the Cavaliers as the most likely winner of the Cavaliers vs. Clippers game.

This prediction follows the latest NBA Injury Report, which suggests the Clippers lineup will feature stars like Kawhi Leonard, John Collins and Jordan Miller, while the Cavaliers will look to Donovan Mitchell, Jaylon Tyson and Jarrett Allen.

This article offers further insights into Wednesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Cavs vs. Clippers prediction: Who will win and cover?

Using trusted machine learning and data analysis, we have simulated the result of Wednesday's NBA game between the Cavaliers and Clippers 10,000 times as part of our NBA predictions coverage.

Our famous predictive model currently gives the Cavaliers a 62% chance of beating the Clippers. Our predicted final score has the Cavaliers winning 112-108.

According to our model, the Clippers (+2.5) have a 52% chance of covering the spread, while the over/under total of 221.5 points has a 51% chance of staying under.

 

Cavaliers vs. Clippers odds

We have researched the best NBA odds in America for this game, which are listed here:

Bet Type Cavaliers Clippers
Spread -2.5 (-112) +2.5 (-105)
Moneyline -148 +126
Total o221.5 (-105) u221.5 (-110)

All odds are correct at the time of publication and are subject to change.

Cavaliers vs. Clippers picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Clippers +2.5 -105
Moneyline Cavaliers -148
Total Under 221.5 -110

According to our best NBA bets for Wednesday, the top play to make on this game is Clippers +2.5 at the spread.

 

Cavaliers vs. Clippers player props

NBA prop bets are a popular way to wager on the Cleveland vs. LA Clippers game without necessarily betting on the outcome. We use the best information available to project how each team's leading players will perform at Intuit Dome.

Donovan Mitchell is expected to lead the Cavaliers with 29 points, 5 rebounds and 6 assists, while Kawhi Leonard is projected to have 27 points, 6 rebounds and 4 assists for the Clippers.

Donovan Mitchell 2026.
Donovan Mitchell is projected to score 29 points tonight.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and today's NBA first basket picks.

Cavaliers prediction

Our model's projected player stats for the Cavaliers are:

Player PTS REB AST 3PM DFS
D. Mitchell 29 5 6 4 52
Jaylon Tyson 16 6 3 2 33
Jarrett Allen 15 9 2 0 34
Sam Merrill 12 3 3 3 24
Dennis Schroder 10 2 4 1 21

Clippers prediction

Projected points, rebounds, assists and three-pointers made for the Clippers:

Player PTS REB AST 3PM DFS
Kawhi Leonard 27 6 4 3 48
John Collins 17 6 2 2 32
Jordan Miller 12 4 2 1 26
Kobe Sanders 11 4 3 2 24
Brook Lopez 10 4 2 3 24

Cavs vs. Clippers game-day updates and essential details

Wednesday's matchup between the Clippers and Cavaliers at Intuit Dome is scheduled to start at 10:30 PM ET.

Conclusion

We predict the Cavaliers, with a 62% win probability, will likely beat the Clippers on Wednesday, with Donovan Mitchell projected for a game-high 52 fantasy points.

AI and automation have enhanced this article to quickly deliver accurate Cavaliers vs. Clippers insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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