Cubs vs. White Sox prediction: Why Cubs are favored to win Sunday's MLB matchup [5/17/2026]

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Written by Jason Bevilacqua

Get Chicago Cubs vs Chicago White Sox predictions for MLB Sunday.

Chicago Cubs-Chicago White Sox Predictions and Game Preview.
Chicago Cubs vs. Chicago White Sox MLB prediction for Sunday, May 17, 2026.

The Chicago White Sox will square off with the Chicago Cubs in MLB action at Rate Field on Sunday, starting at 2:10 PM ET.

Erick Fedde (0-4, 3.77 ERA) will be the starting pitcher for the White Sox, while the Cubs are going with Colin Rea (4-2, 4.68 ERA).

Based on the latest simulation results, Dimers' proven MLB model projects the Cubs as the most likely winner of the Cubs vs. White Sox game.

This article offers a closer look at Sunday's matchup, including best bets and picks.

Cubs vs. White Sox prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the result of Sunday's MLB game between the Cubs and White Sox, forming part of our MLB predictions coverage.

Our leading predictive model currently gives the Cubs a 55% chance of beating the White Sox.

According to our model, the White Sox (+1.5) have a 57% chance of covering the run line, while the over/under total of nine runs has a 51% chance of going over.

 

Cubs vs. White Sox odds [5/17/2026]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type Cubs White Sox
Run Line -1.5 (+129) +1.5 (-152)
Moneyline -132 +114
Total o9 (-111) u9 (-105)

All odds are correct at the time of publication and are subject to change.

Cubs vs. White Sox picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Run Line Cubs -1.5 +129
Moneyline White Sox +114
Total Over 9 -111

According to our MLB best bets, the top play to make on this game is Cubs -1.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Cubs vs. White Sox game-day updates and essential details

Sunday's MLB game between the White Sox and Cubs at Rate Field is scheduled to begin at 2:10 PM ET.

Conclusion

We predict the Cubs, with a 55% win probability, will likely beat the White Sox in Sunday's MLB matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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