Cubs vs. White Sox prediction: Why Cubs are favored to win Sunday's MLB matchup [5/17/2026]
Get Chicago Cubs vs Chicago White Sox predictions for MLB Sunday.

The Chicago White Sox will square off with the Chicago Cubs in MLB action at Rate Field on Sunday, starting at 2:10 PM ET.
Erick Fedde (0-4, 3.77 ERA) will be the starting pitcher for the White Sox, while the Cubs are going with Colin Rea (4-2, 4.68 ERA).
Based on the latest simulation results, Dimers' proven MLB model projects the Cubs as the most likely winner of the Cubs vs. White Sox game.
This article offers a closer look at Sunday's matchup, including best bets and picks.
Cubs vs. White Sox prediction: Who will win and cover?
Our leading predictive model currently gives the Cubs a 55% chance of beating the White Sox.
According to our model, the White Sox (+1.5) have a 57% chance of covering the run line, while the over/under total of nine runs has a 51% chance of going over.
Cubs vs. White Sox odds [5/17/2026]
We have researched the best MLB odds in America for this game, which are listed here:
| Bet Type | Cubs | White Sox |
|---|---|---|
| Run Line | -1.5 (+129) | +1.5 (-152) |
| Moneyline | -132 | +114 |
| Total | o9 (-111) | u9 (-105) |
All odds are correct at the time of publication and are subject to change.
Cubs vs. White Sox picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Cubs -1.5 | +129 |
| Moneyline | White Sox | +114 |
| Total | Over 9 | -111 |
According to our MLB best bets, the top play to make on this game is Cubs -1.5 at the spread.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Cubs vs. White Sox game-day updates and essential details
Sunday's MLB game between the White Sox and Cubs at Rate Field is scheduled to begin at 2:10 PM ET.
- Who: Chicago Cubs vs. Chicago White Sox
- Date: Sunday, May 17, 2026
- Time: 2:10 PM ET/11:10AM PT
- Venue: Rate Field
Conclusion
We predict the Cubs, with a 55% win probability, will likely beat the White Sox in Sunday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.



