Burnley vs. Manchester City prediction, odds, Premier League picks [4/22/2026]

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Written by Nick Slade

Get Burnley vs Manchester City predictions for Premier League Wednesday.

Burnley-Manchester City Predictions and Game Preview.
Burnley vs. Manchester City Premier League prediction for Wednesday, April 22, 2026.

Burnley and Manchester City will lock horns in the Premier League at Turf Moor on Wednesday, starting at 3:00 PM ET.

Based on the latest simulations, Dimers' proven Premier League model projects Manchester City as the most likely winner of the Burnley vs. Manchester City game.

This article offers a closer look at Wednesday's match, including best bets and picks.

Burnley vs. Manchester City prediction: Who will win?

Using powerful machine learning and data, we have simulated the result of Wednesday's Premier League match between Burnley and Manchester City, forming part of our Premier League predictions coverage.

Our independent predictive model suggests a 6.9% chance of Burnley winning, an 80.5% chance for Manchester City, and a 12.6% chance of a draw.

Additionally, the over/under total of 2.5 goals has a 69% chance of going over, according to our model.

 

Burnley vs. Manchester City odds

We have researched the best Premier League odds in America for this game, which are listed here:

Moneyline

Burnley Manchester City Draw
+1800 -625 +800

Total Goals

Over 2.5 Under 2.5
-275 +220

All odds are correct at the time of publication and are subject to change.

Burnley vs. Manchester City picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Moneyline Burnley +1800
Total Goals Under 2.5 +220

According to our Premier League best bets, the top play to make on this game is Burnley to win.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Burnley vs. Manchester City: Correct score and BTTS predictions

Here are the top three most likely final scores according to our model, with a 2-0 Manchester City win being the most probable:

Final Score Probability
BUR 0-2 MCI 11.5%
BUR 0-3 MCI 10.8%
BUR 1-2 MCI 8.3%

When it comes to the both teams to score (BTTS) market, we project a 48.5% chance of both Burnley and Manchester City finding the net and a 51.5% chance that at least one doesn’t.

Burnley vs. Manchester City game-day updates and essential details

Wednesday's Premier League action between Burnley and Manchester City at Turf Moor is scheduled to commence in the United States at 3:00 PM ET.

  • Who: Burnley vs. Manchester City
  • Date: Wednesday, April 22, 2026
  • Time: 3:00 PM ET/12:00PM PT
  • Venue: Turf Moor

Conclusion

According to our computer model, Burnley has a 6.9% win probability on Wednesday, Manchester City has an 80.5% win probability, and there is a 12.6% chance that the game will end in a draw.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Nick Slade
Chief Content Officer

Nick Slade, with nearly two decades of experience, is the Chief Content Officer at Cipher Sports Technology Group, overseeing content for Dimers. He specializes in soccer, NBA, and NHL betting, leveraging predictive analytics and machine learning to provide accurate betting insights.

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