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BYU vs. Iowa State prediction: Why Iowa State is favored to win in college football Week 9, 2025

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Written by Mac Douglass

Get BYU vs Iowa State predictions for college football Saturday.

BYU-Iowa State Predictions and Game Preview.
BYU vs. Iowa State college football gameday prediction for Saturday, October 25, 2025.

Iowa State and Brigham Young will clash in Week 9 college football action at Jack Trice Stadium on Saturday, starting at 3:30PM ET.

Based on the latest simulations, Dimers' advanced college football model predicts the Iowa State as the most likely winner of the BYU vs. Iowa State game.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

BYU vs. Iowa State prediction: Who will win, cover the spread?

Using trusted machine learning and data analysis, we have simulated the result of BYU vs. Iowa State 10,000 times as part of our college football predictions coverage.

Our independent predictive model gives Iowa State a 60% chance of defeating Brigham Young. Our predicted final score has Iowa State winning 26-22.

According to our model, Iowa State (-3) has a 56% chance of covering the spread, while the over/under total of 48.5 points has an equal 50-50 chance of hitting.

 

BYU vs. Iowa State odds

We have researched the best college football odds in America for this game, which are listed here:

Bet Type BYU Iowa State
Spread +3 (-110) -3 (-110)
Moneyline +130 -142
Total o48.5 (-112) u48.5 (-105)

All odds are correct at the time of publication and are subject to change.

BYU vs. Iowa State picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Iowa State -3 -110
Moneyline Iowa State -142
Total Under 48.5 -105

According to our college football best bets, the top play to make on this game is Iowa State -3 at the spread.

 

BYU vs. Iowa State game-day updates and essential details

Saturday's college football game between Iowa State and BYU at Jack Trice Stadium is scheduled to begin at 3:30PM ET.

  • Who: Brigham Young vs. Iowa State
  • Date: Saturday, October 25, 2025
  • Time: 3:30PM ET/12:30PM PT
  • Venue: Jack Trice Stadium

Conclusion

We predict Iowa State, with a 60% win probability, will likely beat Brigham Young on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Brigham Young vs. Iowa State insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on college football

Stay up-to-date with the latest college football news and CFB parlay picks throughout the season. Plus, our College Football National Championship odds offer the most up-to-date probabilities for the national title game and major conferences.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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