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Boston College vs. Syracuse prediction: Syracuse favored to win in college football Week 14, 2025

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Written by Mac Douglass

Get Boston College vs Syracuse predictions for college football Saturday.

Boston College-Syracuse Predictions and Game Preview.
Boston College vs. Syracuse college football gameday prediction for Saturday, November 29, 2025.

Syracuse and Boston College will lock horns in Week 14 college football action at JMA Wireless Dome on Saturday, with kickoff at 3:00PM ET.

Based on updated simulation results, Dimers' proven college football model gives Syracuse a slight edge with a 52% win probability over Boston College.

This article offers an expanded analysis of Saturday's Boston College vs. Syracuse matchup, including an expanded look at the predicted score, best bets and picks.

Boston College vs. Syracuse prediction: Who will win and cover?

Using powerful machine learning and statistical analysis, we have simulated the result of Boston College vs. Syracuse 10,000 times as part of our college football predictions coverage.

Our independent predictive model currently gives Syracuse a 52% chance of beating Boston College. Our predicted final score has Syracuse winning 27-26.

According to our model, Syracuse (+2.5) has a 55% chance of covering the spread, while the over/under total of 54.5 points has a 52% chance of staying under.

 

Boston College vs. Syracuse odds

We have researched the best college football odds in America for this game, which are listed here:

Bet Type Boston College Syracuse
Spread -2.5 (-115) +2.5 (+102)
Moneyline -144 +124
Total o54.5 (-105) u54.5 (-115)

All odds are correct at the time of publication and are subject to change.

Boston College vs. Syracuse picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Syracuse +2.5 +102
Moneyline Syracuse +124
Total Under 54.5 -115

According to our college football best bets, the top play to make on this game is Syracuse to win.

 

Boston College vs. Syracuse game-day updates and essential details

Saturday's college football action between Syracuse and Boston College at JMA Wireless Dome is scheduled to start at 3:00PM ET.

  • Who: Boston College vs. Syracuse
  • Date: Saturday, November 29, 2025
  • Time: 3:00PM ET/12:00PM PT
  • Venue: JMA Wireless Dome

 

Sports betting deal available for NCAAF Saturday

To make the most of the upcoming Missouri launch, check out details on the latest Bet365 bonus code "DIMERS" that unlocks the best opening offer in the game. Don't miss out!

Conclusion

We predict Syracuse, with a 52% win probability, will likely beat Boston College on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Boston College vs. Syracuse insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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