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Arkansas vs. LSU prediction: LSU favored to win in college football Week 12, 2025
Get Arkansas vs LSU predictions for college football Saturday.

LSU will face Arkansas in Week 12 college football action at Tiger Stadium on Saturday, commencing at 12:45PM ET.
Based on the latest simulation results, Dimers' proven college football model predicts LSU as the most likely winner of the Arkansas vs. LSU game.
This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
Arkansas vs. LSU prediction: Who will win and cover?
Using trusted machine learning and data, we have simulated the outcome of Arkansas vs. LSU 10,000 times as part of our college football predictions coverage.
Our leading predictive model gives LSU a 57% chance of beating Arkansas. Our predicted final score has LSU winning 29-26.
According to our model, Arkansas (+4.5) has a 59% chance of covering the spread, while the 58.5-point over/under has a 51% chance of going over.
Arkansas vs. LSU odds
We have sourced the best College Football odds in America for this game, which are listed here:
| Bet Type | Arkansas | LSU |
|---|---|---|
| Spread | +4.5 (-110) | -4.5 (-110) |
| Moneyline | +156 | -185 |
| Total | o58.5 (-105) | u58.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Arkansas vs. LSU picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Arkansas +4.5 | -110 |
| Moneyline | Arkansas | +156 |
| Total | Over 58.5 | -105 |
According to our college football best bets, the top play to make on this game is Arkansas +4.5 at the spread.
Arkansas vs. LSU game-day updates and essential details
Saturday's college football action between LSU and Arkansas at Tiger Stadium is scheduled to commence at 12:45PM ET.
- Who: Arkansas vs. LSU
- Date: Saturday, November 15, 2025
- Time: 12:45PM ET/9:45AM PT
- Venue: Tiger Stadium
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Conclusion
We predict LSU, with a 57% win probability, will likely beat Arkansas on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Arkansas vs. LSU insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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