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Diamondbacks vs. Dodgers prediction: Dodgers favored to win MLB Opening Day matchup [3/26/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Arizona Diamondbacks vs Los Angeles Dodgers predictions for MLB Thursday.
The Los Angeles Dodgers will face the Arizona Diamondbacks on Opening Day of the 2022 MLB season at UNIQLO Field at Dodger Stadium on Thursday, commencing at 8:30 PM ET.
Yoshinobu Yamamoto (0-0, 0.00 ERA) will be the starting pitcher for the Dodgers, while the Diamondbacks are going with Zac Gallen (0-0, 0.00 ERA).
Based on updated simulation results, Dimers' refined MLB model predicts the Dodgers as the most likely winner of the Diamondbacks vs. Dodgers game.
This article offers a closer look at Thursday's matchup, including best bets and picks.
Diamondbacks vs. Dodgers prediction: Who will win on MLB Opening Day?
Using trusted machine learning and data analysis, we have simulated the result of Thursday's MLB matchup between the Diamondbacks and Dodgers, forming part of our MLB predictions coverage.
Our leading predictive model currently gives the Dodgers a 68% chance of defeating the Diamondbacks.
According to our model, the Dodgers (-1.5) have a 53% chance of covering the run line, while the over/under total of nine runs has a 52% chance of going over.
Diamondbacks vs. Dodgers odds [3/26/2026]
We have researched the best MLB odds in America for this game, which are listed here:
| Bet Type | Diamondbacks | Dodgers |
|---|---|---|
| Run Line | +1.5 (+113) | -1.5 (-130) |
| Moneyline | +229 | -260 |
| Total | o9 (-104) | u9 (-110) |
All odds are correct at the time of publication and are subject to change.
Diamondbacks vs. Dodgers picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Diamondbacks +1.5 | +113 |
| Moneyline | Diamondbacks | +229 |
| Total | Over 9 | -104 |
According to our MLB best bets, the top play to make on this game is Diamondbacks to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Diamondbacks vs. Dodgers game-day updates and essential details
Thursday's MLB game between the Dodgers and Diamondbacks at UNIQLO Field at Dodger Stadium is scheduled to begin at 8:30 PM ET.
- Who: Arizona Diamondbacks vs. Los Angeles Dodgers
- Date: Thursday, March 26, 2026
- Time: 8:30 PM ET/5:30PM PT
- Venue: UNIQLO Field at Dodger Stadium
Conclusion
We predict the Dodgers, with a 68% win probability, will likely beat the Diamondbacks on Thursday.
AI and automation have enhanced this article to quickly deliver accurate Diamondbacks vs. Dodgers insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice, head to our responsible gambling hub.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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