Alexei Popyrin vs. Alexandre Muller prediction, odds, picks for 2026 Australian Open

Alexei Popyrin will square off with Alexandre Muller in the first round of the 2026 Australian Open on Monday.

Based on updated simulation results, Dimers' proven tennis model projects Alexei Popyrin as the most likely winner of the Popyrin vs. Muller match.

This article offers an expanded analysis of Monday's match, including best bets and picks.

Popyrin vs. Muller prediction: Who will win and advance to the second round?

Using innovative machine learning and statistical analysis, we have simulated the result of Monday's Popyrin-Muller men's singles match 10,000 times as part of our tennis predictions coverage.

Our leading predictive model currently gives Popyrin a 62% chance of winning against Muller in the 2026 Australian Open.

Additionally, Popyrin has a 60% chance of winning the first set. The simulations also show that the bookmakers have got it right with the -3.5 games spread, with each player projected to have a 50-50 chance of covering, while the under 39.5 games has a 55% chance of hitting**, according to our model.

Alexei Popyrin vs. Alexandre Muller odds

We have researched the most up-to-date betting odds in America for this match, which are listed here:

All odds are correct at the time of publication and are subject to change.

Popyrin vs. Muller picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: