Alabama vs. South Carolina prediction: Alabama favored to win in college football Week 9, 2025

South Carolina will face the favored Alabama in Week 9 college football action at Williams-Brice Stadium on Saturday, commencing at 3:30PM ET.

Based on updated simulations, Dimers' proven college football model predicts the Alabama as the most likely winner of the Alabama vs. South Carolina game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Alabama vs. South Carolina prediction: Who will win, cover the spread?

Using powerful machine learning and data, we have simulated the outcome of Alabama vs. South Carolina 10,000 times as part of our college football predictions coverage.

Our independent predictive model currently gives Alabama an 80% chance of defeating South Carolina. Our predicted final score has Alabama winning 30-18.

According to our model, South Carolina (+11.5) has a 51% chance of covering the spread, while the 47.5-point over/under has a 53% chance of staying under.

Alabama vs. South Carolina odds

We have sourced the best college football odds in America for this game, which are listed here:

Bet Type	Alabama	South Carolina
Spread	-11.5 (-105)	+11.5 (-105)
Moneyline	-450	+380
Total	o47.5 (-110)	u47.5 (-102)

All odds are correct at the time of publication and are subject to change.

Alabama vs. South Carolina picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Spread	South Carolina +11.5	-105
Moneyline	South Carolina	+380
Total	Under 47.5	-102

According to our college football best bets, the top play to make on this game is Under 47.5 total points.

Alabama vs. South Carolina game-day updates and essential details

Saturday's college football game between South Carolina and Alabama at Williams-Brice Stadium is scheduled to start at 3:30PM ET.

• Who: Alabama vs. South Carolina
• Date: Saturday, October 25, 2025
• Time: 3:30PM ET/12:30PM PT
• Venue: Williams-Brice Stadium

Sports betting deal available for NCAAF Saturday

To make the most of Saturday's massive day of sports, headlined by clashes like this one for college football Saturday, check out details on the latest Bet365 bonus code "DIMERS" that unlocks $200 in bonus bets from a $5 bet — win or lose. Don't miss out!

Conclusion

We predict Alabama, with an 80% win probability, will likely beat South Carolina on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Alabama vs. South Carolina insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on college football

Stay informed with the latest college football betting news and CFB parlay picks throughout the season. Plus, our College Football National Championship odds provide the latest probabilities for the national title game and major conferences.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.