Santos Laguna vs. Guadalajara prediction, odds, Liga MX picks [8/16/2026]
Get Santos Laguna vs Guadalajara predictions for Liga MX Sunday.
Santos Laguna will take on Guadalajara in Liga MX action at Estadio Corona on Sunday, commencing at 9:10 PM ET.
Dimers' proven Liga MX model projects Guadalajara as the most likely winner in this Santos Laguna vs. Guadalajara prediction.
This article offers further insights into Sunday's match, including best bets and picks.
Santos Laguna vs. Guadalajara prediction: Who will win?
Our independent predictive model indicates a 19.1% chance of Santos Laguna winning, a 58.3% chance for Guadalajara, and a 22.6% chance of a draw.
Additionally, the 2.5-goal over/under has a 52.7% chance of going over, with a 51.5% probability that both teams score.
Santos Laguna vs. Guadalajara odds
We have researched the best Liga MX odds in America for this game, which are listed here:
- Moneyline: Guadalajara -190, Santos Laguna +500
All odds are correct at the time of publication and are subject to change.
Santos Laguna vs. Guadalajara picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
- Moneyline: Santos Laguna @ +500 via DraftKings
- Total Goals: Under 2.5 @ +135 via Bet365
According to our Liga MX best bets, the top play to make on this game is Under 2.5 total goals.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Santos Laguna vs. Guadalajara: Correct score and BTTS predictions
The top three most likely final scores, according to our model, are listed below, with a 1-0 Guadalajara win being the most probable:
- Santos Laguna 0-1 Guadalajara (11.3% probability)
- Santos Laguna 1-1 Guadalajara (10.7%)
- Santos Laguna 0-2 Guadalajara (10.4%)
When it comes to the both teams to score (BTTS) market, we project a 51.5% chance of both sides finding the net and a 48.5% chance that at least one doesn’t.
Santos Laguna vs. Guadalajara game-day updates and essential details
Sunday's action between Santos Laguna and Guadalajara at Estadio Corona is scheduled to commence at 9:10 PM ET.
- Who: Santos Laguna vs. Guadalajara
- Date: Sunday, August 16, 2026
- Time: 9:10 PM ET/6:10PM PT
- Venue: Estadio Corona
Conclusion
According to our computer model, Santos Laguna has a 19.1% win probability on Sunday, Guadalajara has a 58.3% win probability, and there is a 22.6% chance that the game will end in a draw.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
