Vikings vs. 49ers Preview and Prediction

Our Vikings vs. 49ers preview, analysis and predictions for November 22, 2026, are based on 10,000 NFL game simulations. See Dimers Pro for unlimited access.
NFL
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NFL
Vikings
Predicted score
22
:
25
Nov 22, 8:20 PM ET Estadio Banorte
49ers
Nov 22, 8:20 PM ET Estadio Banorte
Pre-Game Probabilities Last Update: May 18, 2026, 10:33 PM ET

Spread

Vikings +4.5
Spread
  • Vikings
    58.9%
    bet365bet365
  • 49ers
    41.1%
    FanDuelFanDuel

Vikings vs. 49ers: Detailed Breakdown

Matchup Overview

Current Betting Odds

  • Spread: 49ers favored at -4.5
  • Total (Over/Under): 46.5
  • Moneyline Odds: Vikings +185, 49ers -192

Dimers' Win Probabilities

  • Vikings: 38%
  • 49ers: 62%

Dimers' predictive NFL model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Projected Final Score

Our predicted final score for this NFL matchup is Vikings 22-25 49ers.

This prediction is based on each team's average score and player stats following 10,000 game simulations.

Our Prediction: Who Wins?

After extensive simulations, our model gives the Vikings a win probability of 38%, while the 49ers have a win probability of 62%.

Summary

The Vikings face off against the 49ers in the NFL at Estadio Banorte on Sunday, November 22, 2026. On this page, you'll find our preview, analysis and data-driven projections for the game.

Our Vikings vs. 49ers predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

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