Cardinals vs. Chiefs: NFL Week 11 Prediction, Picks & Odds

Dimers' Cardinals vs. Chiefs prediction for Sunday, November 22, 2026. Win probabilities, projected final score, current odds, and picks from our NFL machine learning models.
NFL
NFL sport icon
NFL
Cardinals
Predicted score
17
:
28
Arrowhead Stadium
Chiefs
Arrowhead Stadium
Pre-Game Probabilities Last updated:

Spread

Cardinals +11.5
Spread
  • Cardinals
    50.0%
    CaesarsCaesars
  • Chiefs
    50.0%
    CaesarsCaesars

Cardinals vs. Chiefs: Detailed Breakdown

Matchup overview: NFL Week 11

  • Teams: Arizona Cardinals vs. Kansas City Chiefs
  • Date: Sunday, November 22, 2026
  • Time: 1:00PM ET
  • Venue: Arrowhead Stadium

Current betting odds

  • Spread: Cardinals (+11.5, -115), Chiefs (-11.5, -115)
  • Moneyline: Cardinals +450, Chiefs -650
  • Total (Over/Under): 45.5 points (-115/-115)

Dimers’ win probabilities

  • Cardinals: 16.7%
  • Chiefs: 83.3%

These probabilities come from two machine learning models that assess more than 100 data points for each NFL matchup, combining their outputs to project all our major betting markets.

Projected final score

Our predicted final score for this NFL matchup is Cardinals 16-28 Chiefs.

This prediction draws on each team's scoring trends and player stats, weighed across both of our data models

Our Prediction: Who Wins?

The numbers give the Cardinals a win probability of 16.7%, while the Chiefs have a win probability of 83.3%.

Summary

The Cardinals face off against the Chiefs in the NFL at Arrowhead Stadium on Sunday, November 22, 2026.

Our Cardinals vs. Chiefs predictions, built on real-time data and matchup-specific modeling, help guide your decisions. Remember to bet responsibly and within your financial limits.

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For further insights, explore our expert NFL predictions and the best NFL bets today, while our in-depth analysis includes NFL props, NFL futures, NFL odds, and the latest NFL news.