Virginia vs. Syracuse CFB Prediction and Odds - Sep 23, 2022

Syracuse faces Virginia in College Football action at JMA Wireless Dome on Friday, starting at 7:00PM ET.

Dimers' free betting picks for Virginia vs. Syracuse, as well as our score prediction and best odds, are detailed below.

Today's Virginia vs. Syracuse betting analysis is sponsored by DraftKings Sportsbook, which has an outstanding Bet $5, Win $200 promo for new users.


Who will win Virginia vs. Syracuse?

Based on trusted machine learning and data, has simulated Virginia vs. Syracuse 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, gives Syracuse a 70% chance of defeating Virginia.

More: Virginia vs. Syracuse Simulated 10,000 Times

Virginia vs. Syracuse Game Odds

  • Spread: Syracuse -9.5 (-107), Virginia +9.5 (-105)
  • Moneyline: Syracuse -350, Virginia +320
  • Total: Over/Under 53.5 (-107/-104)

Point Spread, Moneyline and Over/Under

Syracuse is listed as the -9.5 favorite versus Virginia, with -107 at PointsBet the best odds currently available.

For the underdog Virginia (+9.5) to cover the spread, FanDuel Sportsbook has the best odds currently on offer at -105.

PointsBet currently has the best moneyline odds for Syracuse at -350, which means you can risk $350 to win $100, for a total payout of $450, if it gets the W.

Meanwhile, FanDuel Sportsbook currently has the best moneyline odds for Virginia at +320, where you can bet $100 to profit $320, earning a total payout of $420, if it wins.

The Over/Under sits at 53.5 with PointsBet, which currently has the best odds for the Over at -107, while FanDuel Sportsbook currently has the best odds for the Under at -104.

As always, make sure you check the sportsbooks you have access to in your state for the best College Football odds and lines.

According to DimersBOT, Virginia (+9.5) is a 52% chance of covering the spread, while the 53.5-point Over/Under is a 55% chance of going Under.

More: Track Your Bets via Bet Center

Best Bets for Virginia vs. Syracuse


Every time you see a πŸ”₯, you know it's one of our best free picks today across any sport.

Dimers' best bets are based on world-class modeling and betting expertise to help you make smarter decisions with your state's legal sportsbooks.

While Syracuse is more likely to win the game, according to DimersBOT, betting on Virginia moneyline is the best option because of the 6.2% edge identified when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges seen here at is crucial to being profitable in the long run.

Virginia vs. Syracuse Prediction's predicted final score for Virginia vs. Syracuse at JMA Wireless Dome this Friday has Syracuse winning 29-21.

Click or tap on See Matchup for more.


Dimers has full betting coverage of this week's Virginia-Syracuse matchup, including pregame predictions, best betting picks, and live win probabilities.

Don't forget, DimersBOT updates often, so check this article for the latest betting analysis before Virginia vs. Syracuse on Friday September 23, 2022.


Virginia vs. Syracuse 2022 CFB Game Info

Friday's matchup between Syracuse and Virginia in College Football at JMA Wireless Dome is scheduled to begin at 7:00PM ET.

  • Who: Virginia vs. Syracuse
  • Date: Friday September 23, 2022
  • Time: 7:00PM ET / 4:00PM PT
  • Venue: JMA Wireless Dome

Want to join an online sportsbook and start betting on College Football today? Check out the top sportsbook sign-up offers in your state.

What College Football games are on this week?

Virginia and Syracuse aren't the only two NCAA Football teams you can bet on today. DimersBOT never stops and we've got picks and top bets for each and every CFB matchup via our College Football Predictions section.

Not only do we provide with you first-class predictions, but we also have recommended bets for the Spread, Over/Under and Moneyline. Sound good? Check it out now!

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