Get San Antonio Spurs vs Minnesota Timberwolves predictions for NBA Playoffs Friday.
San Antonio Spurs vs. Minnesota Timberwolves NBA prediction for Game 6 of the series.
The Minnesota Timberwolves will square off with the favored San Antonio Spurs in Game 6 of their 2026 NBA Playoffs series at Target Center on Friday, starting at 9:30 PM ET.
Based on updated simulations and today’s injury updates, Dimers' advanced NBA model projects the Spurs as the most likely winner of the Spurs vs. Timberwolves Game 6 matchup.
This prediction follows the latest NBA Injury Report, which suggests the Timberwolves lineup will feature stars like Anthony Edwards, Julius Randle and Jaden McDaniels, while the Spurs will be led by Victor Wembanyama, De'Aaron Fox and Stephon Castle.
This article offers an expanded analysis of Friday's matchup, including an expanded look at the predicted score, best bets and player prop picks.
Spurs vs. Wolves prediction: Who will win Game 6?
Using innovative machine learning and data, we have simulated the result of Friday's NBA Playoffs matchup between the Spurs and Timberwolves, forming part of our NBA predictions coverage.
Our independent predictive model gives the Spurs a 72% chance of beating the Timberwolves in Game 6 of the series. Our predicted final score has the Spurs winning 112-106.
According to our model, the Spurs (-5.5) have a 53% chance of covering the spread, while the 219.5-point over/under has an equal 50-50 chance of hitting.
Spurs vs. Timberwolves Game 6 odds
We have researched the best NBA odds in America for this game, which are listed here:
Bet Type
Spurs
Timberwolves
Spread
-5.5 (-110)
+5.5 (-108)
Moneyline
-218
+188
Total
o219.5 (-105)
u219.5 (-115)
All odds are correct at the time of publication and are subject to change.
Spurs vs. Timberwolves picks and best bet for Game 6
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
According to our NBA best bets, the top play to make on this game is Spurs to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Spurs vs. Timberwolves Game 6 player props
NBA prop bets are an exciting way to wager on the San Antonio vs. Minnesota game without necessarily betting on the outcome. We have crunched the numbers to project how each team's leading players will perform at Target Center.
Victor Wembanyama is expected to lead the Spurs with 27 points, 13 rebounds and 3 assists, while Anthony Edwards is projected to have 28 points, 6 rebounds and 4 assists for the Timberwolves.
Anthony Edwards is projected to score 28 points tonight.
The NBA Playoffs is an annual elimination tournament held to determine the league's champion.
A total of 16 teams, including the Spurs and Timberwolves, reached the NBA Playoffs 2026, which includes four rounds: the First Round, Conference Semifinals, Conference Finals, and NBA Finals.
Each round is played as a best-of-seven series, with the first team to four wins progressing to the next round until a champion is crowned.
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Conclusion
We predict the Spurs, with a 72% win probability, will likely beat the Timberwolves in Friday's NBA playoffs matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
