Red Sox vs. Yankees Prediction and Odds - Sep 22, 2022

The New York Yankees face the Boston Red Sox in MLB action at Yankee Stadium on Thursday, commencing at 7:15PM ET.

The Yankees will send Jameson Taillon (13-5, 4.04 ERA) to the mound, while the Red Sox are going with Michael Wacha (11-1, 2.60 ERA).

Dimers' free betting picks for Red Sox vs. Yankees, as well as game predictions and betting odds, are detailed below.


Who will win Red Sox vs. Yankees?

Using advanced machine learning and data, has simulated Thursday's Red Sox-Yankees MLB game 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, currently gives the Yankees a 62% chance of defeating the Red Sox.

More: Full Betting Analysis for Red Sox vs. Yankees

Red Sox vs. Yankees Odds

  • Run Line: Yankees -1.5 (+135), Red Sox +1.5 (-152)
  • Moneyline: Yankees -150, Red Sox +130
  • Total: Over/Under 8 (-110/+105)

Run Line, Moneyline and Over/Under

The Yankees are currently -1.5 favorites against the Red Sox, with +135 at BetMGM the best odds currently available.

For the underdog Red Sox (+1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at -152.

BetMGM currently has the best moneyline odds for the Yankees at -150. That means you can risk $150 to win $100, for a total payout of $250, if they get the W.

On the other hand, DraftKings Sportsbook currently has the best moneyline odds for the Red Sox at +130, where you can bet $100 to profit $130, earning a total payout of $230, if they win.

The Over/Under is set at 8 with BetMGM, which currently has the best odds for the Over at -110, while Caesars Sportsbook currently has the best odds for the Under at +105.

As always, make sure you check the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Red Sox (+1.5) are a 60% chance of covering the run line, while the 8-run Over/Under is a 56% chance of going Over.

More: Free Prop Picks

Best Bets for Red Sox vs. Yankees

  • Run Line: Red Sox +1.5 @ -152 via FanDuel Sportsbook (60% probability)
  • Moneyline: Yankees @ -150 via BetMGM (62% probability)
  • Total: Over 8 @ -110 via BetMGM (56% probability)


Our best bets are based on detailed modeling and gambling expertise to help you make better decisions with your state's legal sportsbooks.

Red Sox vs. Yankees Prediction

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Dimers has full coverage of Thursday's Red Sox-Yankees matchup, including pregame predictions, computer picks, and live win probabilities.

Remember, DimersBOT updates regularly, so check this article for any changes to our betting analysis before Red Sox vs. Yankees on Thursday September 22, 2022.


Red Sox vs. Yankees 2022 Game Info

Thursday's action between the Yankees and Red Sox at Yankee Stadium is scheduled to begin at 7:15PM ET.

  • Who: Boston Red Sox vs. New York Yankees
  • Date: Thursday September 22, 2022
  • Time: 7:15PM ET / 4:15PM PT
  • Venue: Yankee Stadium

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Finally, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities matched against the best odds to win the World Series.

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