• NBA
  • NHL
  • College Football
  • World Cup 2022
  • College Basketball
  • Tennis
  • Golf
  • Premier League
  • La Liga

Rays vs. Guardians Prediction and Odds - Sep 29, 2022

The Cleveland Guardians and Tampa Bay Rays are scheduled to meet in MLB at Progressive Field on Thursday, starting at 6:10PM ET.

Cal Quantrill (14-5, 3.49 ERA) will get the ball for the Guardians, while the Rays will counter with Jeffrey Springs (9-4, 2.56 ERA).

Dimers' top betting picks for Rays vs. Guardians, as well as game predictions and best odds, are detailed in this article.


Who will win Rays vs. Guardians?

Using trusted computer power and data, Dimers.com has simulated Thursday's Rays-Guardians MLB matchup 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, currently gives the Rays a 52% chance of getting the W against the Guardians.

More: Rays vs. Guardians Simulated 10K Times

Rays vs. Guardians Odds

  • Run Line: Guardians +1.5 (-165), Rays -1.5 (+145)
  • Moneyline: Guardians +115, Rays -130
  • Total: Over/Under 6.5 (-105/-110)

Run Line, Moneyline and Over/Under

The Guardians are +1.5 underdogs versus the Rays, with -165 at BetMGM the best odds currently available.

For the favored Rays (-1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at +145.

DraftKings Sportsbook currently has the best moneyline odds for the Guardians at +115, which means you can bet $100 to profit $115, earning a total payout of $215, if they win.

Meanwhile, BetMGM currently has the best moneyline odds for the Rays at -130, where you can risk $130 to win $100, for a total payout of $230, if they come out on top.

The Over/Under for total runs scored sits at 6.5 with BetMGM, which currently has the best odds for the Over at -105, while Caesars Sportsbook currently has the best odds for the Under at -110.

As always, check out the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Guardians (+1.5) are a 62% chance of covering the run line, while the 6.5-run Over/Under is a 59% chance of going Over.

More: Track Your Bets via Dimers' Bet Center

Best Bets for Rays vs. Guardians


When you see a 🔥, you know it's one of our best free picks of the day across any sport.

Dimers' best bets are based on detailed modeling and gambling expertise to bring you the best possible plays 24/7.

While the Rays are more likely to win the game, according to DimersBOT, taking the Guardians moneyline is the best option because of the 1.5% edge identified when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges published on Dimers is crucial to being profitable in the long run.

Rays vs. Guardians Probabilities

Click or tap on See Matchup to reveal more.


Dimers has full coverage of Thursday's Rays-Guardians matchup, including pregame predictions, free picks, and live win probabilities.

Remember, DimersBOT updates regularly, so keep checking this page for any changes to our betting insights before Rays vs. Guardians on Thursday September 29, 2022.


Rays vs. Guardians 2022 Game Info

Thursday's matchup between the Guardians and Rays at Progressive Field is scheduled to start at 6:10PM ET.

  • Who: Tampa Bay Rays vs. Cleveland Guardians
  • Date: Thursday September 29, 2022
  • Time: 6:10PM ET / 3:10PM PT
  • Venue: Progressive Field

Want to join an online sportsbook and start betting on MLB? Check out the best sportsbook bonus offers in your state.

Want more MLB predictions like this?

To get more MLB betting previews like you've just read for Rays vs. Guardians, all you've gotta do is visit Dimers' MLB Betting News page. It's that easy – they're all there!

We use the power of predictive analytics to find value in the markets so we can publish the most comprehensive MLB betting previews out there. We do this by comparing our own probabilities against the sportsbooks' odds (aka Vegas odds) as soon as they go live.

So, get ahead of the game and beat the bookies today – it's only a click away.

While you're here, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities compared to the best odds to win the World Series.

Related Articles
More Articles