Manchester United vs. Southampton Prediction, Odds, Premier League Picks [1/16/2025]

Premier League action continues on Thursday at 3:00PM ET as Southampton takes on Manchester United at Old Trafford.

Based on the latest simulation results, Dimers' advanced Premier League model (see Dimers Pro for full access) projects Manchester United as the most likely winner of the game.

"Using the latest data, our experts simulated Thursday's Manchester United-Southampton game 10,000 times," said Jason Bevilacqua from Dimers.

"After incorporating the most recent updates and numerous additional inputs, our prediction gives Manchester United a 69.5% chance of winning, Southampton a 12.7% chance, and a 17.8% chance of a draw."

For further insights into Thursday's matchup, including best bets and an expanded look at the predicted final score, visit our interactive Manchester United vs. Southampton predictions page.

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Manchester United vs. Southampton Game-Day Updates and Essential Details

Thursday's Premier League action between Manchester United and Southampton at Old Trafford is scheduled to begin in the USA at 3:00PM ET.

• Who: Manchester United vs. Southampton
• Date: Thursday, January 16, 2025
• Time: 3:00PM ET/12:00PM PT
• Venue: Old Trafford
• Merchandise: Buy Manchester United and Southampton gear at Fanatics

Dimers.com's comprehensive preview of Thursday's Manchester United vs. Southampton matchup includes our prediction, picks and the latest betting odds.

Before making any Southampton vs. Manchester United picks, be sure to check out the latest Premier League predictions and betting advice from Dimers Pro.

Manchester United vs. Southampton Prediction: Who Will Win?

Using trusted machine learning and data, we have simulated the result of Thursday's Premier League match between Manchester United and Southampton 10,000 times as part of our Premier League predictions coverage.

Our leading predictive model currently suggests a 69.5% chance of Manchester United winning, a 12.7% chance for Southampton, and a 17.8% chance of a draw.

Manchester United vs. Southampton Odds

We have sourced the best betting odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Manchester United vs. Southampton Picks

Our model's strongest edge in the Manchester United vs. Southampton matchup is on the moneyline.

Our expert predictions, aligned with the latest odds, reveal the best Premier League picks for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

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Manchester United vs. Southampton: Correct Score Prediction

Here are the top three most likely final scores according to our model, with a 2-0 Manchester United win being the most probable:

These final scores are based on each team's average score after 10,000 simulations.

Conclusion

According to our computer model, Manchester United has a 69.5% win probability on Thursday, Southampton has a 12.7% win probability, and there is a 17.8% chance that the game will end in a draw.

AI and automation have enhanced this article to quickly deliver accurate Manchester United vs. Southampton insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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