Karolina Pliskova vs. Anastasia Potapova prediction, odds, picks for WTA Madrid Open 2026

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Written by Ryan Leaver

Get Pliskova vs Potapova predictions for WTA Madrid Open.

Karolina Pliskova vs Anastasia Potapova Tennis Prediction.
Our Karolina Pliskova and Anastasia Potapova tennis prediction is based on thousands of simulations of the upcoming match.

Karolina Pliskova will square off with Anastasia Potapova in the quarterfinals at the WTA Madrid event on Wednesday.

Based on updated simulation results, Dimers' advanced tennis model predicts Anastasia Potapova as the most likely winner of the Pliskova vs. Potapova match.

This article offers an expanded analysis of Wednesday's match, including best bets and picks.

Pliskova vs. Potapova prediction: Who will win and advance to the semifinals?

Using trusted machine learning and data, we have simulated the result of Wednesday's Pliskova-Potapova women's singles match, forming part of our tennis predictions coverage.

Our leading predictive model gives Potapova a 58% chance of winning against Pliskova at the WTA Madrid Open tournament.

Additionally, Potapova has a 55% chance of winning the first set. The simulations also show Pliskova (+2.5) has a 53% chance of covering the games spread, while the **over/under of 21.5 games has an equal 50-50 chance of hitting, according to our model.

 

Karolina Pliskova vs. Anastasia Potapova odds

We have sourced the most up-to-date betting odds in America for this match, which are listed here:

Bet Type Pliskova Potapova
Moneyline +152 -183
First Set +130 -164
Game Spread +2.5 (-110) -2.5 (-145)
Total Games o21.5 (-118) u21.5 (-110)

All odds are correct at the time of publication and are subject to change.

Pliskova vs. Potapova picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Moneyline Pliskova +152
First Set Potapova -110

According to our best tennis bets, the top play to make on this match is Karolina Pliskova to win.

Although Pliskova is less than likely to win, she provides the best value at the current available odds.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

Pliskova vs. Potapova updates and essential details

The WTA Madrid Open match between Karolina Pliskova and Anastasia Potapova is scheduled to commence on Wednesday at 7:00 AM ET.

  • Who: Karolina Pliskova vs. Anastasia Potapova
  • Date: Wednesday, April 29, 2026
  • Approx. Time: 7:00 AM ET/4:00AM PT
  • Tournament: WTA Madrid, Spain Women's Singles 2026
  • Round: Quarterfinals

All dates and times mentioned in this article are United States Eastern Time unless otherwise noted.

Conclusion

We predict Anastasia Potapova, with a 58% win probability, will likely beat Karolina Pliskova at the WTA Madrid Open tournament.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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