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Clemson vs. Duke CFB Prediction and Odds - September 4, 2023

Duke and Clemson meet in College Football action at Brooks Field at Wallace Wade Stadium on Monday, starting at 8:00PM ET.

Dimers' top betting picks for Clemson vs. Duke, as well as game predictions and betting odds, are detailed in this article.

Today's Clemson vs. Duke betting analysis is proudly sponsored by Bet365, which has a Bet $1, Get $200 in Bonus Bets offer for new users.


Who Will Win: Clemson vs. Duke

Based on cutting-edge computer power and data, Dimers.com has simulated Clemson vs. Duke 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, currently gives Clemson a 78% chance of beating Duke.

More: Betting Analysis for Clemson vs. Duke

Clemson vs. Duke Odds

  • Spread: Duke +12.5 (-110), Clemson -12.5 (-110)
  • Moneyline: Duke +350, Clemson -475
  • Total: Over/Under 54.5 (-110/-105)

Duke is listed as the +12.5 underdog versus Clemson, with -110 at DraftKings Sportsbook the best odds currently available.

For the favored Clemson (-12.5) to cover the spread, PointsBet has the best odds currently on the market at -110.

DraftKings Sportsbook currently has the best moneyline odds for Duke at +350. That means you can bet $100 to profit $350, earning a total payout of $450, if it wins.

Elsewhere, PointsBet currently has the best moneyline odds for Clemson at -475, where you can risk $475 to win $100, for a total payout of $575, if it comes out on top.

The Over/Under is set at 54.5 with DraftKings Sportsbook, which currently has the best odds for the Over at -110, while FanDuel Sportsbook currently has the best odds for the Under at -105.

As always, make sure you check the sportsbooks you have access to in your state for the best College Football odds and lines.

According to DimersBOT, Duke (+12.5) has a 52% chance of covering the spread, while the Over/Under total of 54.5 points has a 54% chance of going Under.

More: Best Prop Bets to Make Today

Best Bets: Clemson vs. Duke


Our best bets are based on world-class simulations and gambling intelligence to help you make better investments with the legal sportsbooks in America.

While Clemson is more likely to win the game, according to DimersBOT, betting on Duke moneyline is the best option due to the edge identified when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges published here at Dimers.com is crucial to achieving long-term profitability.

Clemson vs. Duke Prediction

Dimers.com's predicted final score for Clemson vs. Duke at Brooks Field at Wallace Wade Stadium this Monday has Clemson prevailing 32-20.

Click or tap on See Matchup for more information.


Dimers has full coverage of this week's Clemson-Duke game, including pregame predictions, top betting picks, and live win probabilities.

Don't forget, DimersBOT updates regularly, so keep checking this article for the latest betting analysis ahead of Clemson vs. Duke on Monday September 4, 2023.


Clemson vs. Duke 2023

Monday's action between Duke and Clemson in College Football at Brooks Field at Wallace Wade Stadium is scheduled to start at 8:00PM ET.

  • Who: Clemson vs. Duke
  • Date: Monday September 4, 2023
  • Time: 8:00PM ET / 5:00PM PT
  • Venue: Brooks Field at Wallace Wade Stadium

Ready to join an online sportsbook and start betting on College Football? Check out the top sports betting promos in your state.

Make Smarter Sports Betting Decisions with Dimers

Dimers' picks are made after 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods.

While our Clemson vs. Duke predictions can help you make informed decisions, it's crucial that you only bet what you can afford to lose and manage your bankroll effectively.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

What CFB Games Are on This Week?

Clemson and Duke aren't the only two NCAA Football teams you can bet on today. DimersBOT never stops and we've got picks and best bets for each and every CFB matchup via our College Football predictions. Not only do we provide with you great predictions, but we also have recommended bets for the Spread, Over/Under and Moneyline. Sound good? Check it out now!

In addition to our leading CFB predictions, Dimers also offers the best CFB prop bets today, projecting passing yards, touchdowns, and more against the best odds available every single day of the CFB season.


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