Columbus Crew vs. Charlotte FC prediction, odds, MLS picks [10/14/2026]

Columbus will square off with Charlotte in MLS action at ScottsMiracle-Gro Field on Wednesday, beginning at 7:30 PM ET.

Dimers' advanced MLS model projects Columbus as the most likely winner in this Columbus vs. Charlotte prediction.

This article offers further insights into Wednesday's match, including best bets and picks.

Columbus Crew vs. Charlotte FC prediction and odds

Using trusted machine learning and data, we have re-simulated the result of Wednesday's MLS matchup between Columbus and Charlotte, forming part of our MLS predictions coverage.

Our independent predictive model indicates a 47.1% chance of Columbus winning, a 29.8% chance for Charlotte, and a 23.1% chance of a draw. Additionally, the over/under total of 2.5 goals has a 61.3% chance of going over., according to our model.

Latest betting odds

We have sourced the best MLS odds in America for this game, which are listed here:

• Moneyline: Charlotte +257, Columbus +100
• Total Goals: Over/Under 2.5 (-200/+194)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Moneyline: Charlotte @ +257 via Novig
• Total Goals: Under 2.5 @ +194 via Polymarket

According to our MLS best bets, the top play to make on this game is Under 2.5 total goals.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Correct score projections

The top three most likely final scores, according to our model, are listed below, with a 1-1 draw being the most probable:

• Columbus 1-1 Charlotte (10.4% probability)
• Columbus 2-1 Charlotte (9.3%)
• Columbus 1-0 Charlotte (7.5%)

These predictions are based on each team's average score according to our machine learning model, meaning the most likely correct score may differ from our predicted winner.

Game info & kickoff details

Wednesday's MLS game between Columbus and Charlotte in MLS at ScottsMiracle-Gro Field is scheduled to begin at 7:30 PM ET.

• Who: Columbus Crew vs. Charlotte FC
• Date: Wednesday, October 14, 2026
• Time: 7:30 PM ET/4:30PM PT
• Venue: ScottsMiracle-Gro Field

Conclusion

According to our computer model, Columbus has a 47.1% win probability on Wednesday, Charlotte has a 29.8% win probability, and there is a 23.1% chance that the game will end in a draw.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary MLS prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.