Club America vs. Guadalajara prediction, odds, Liga MX picks [9/19/2026]

Using innovative machine learning and data, we have re-simulated the result of Saturday's Liga MX game between Club America and Guadalajara, forming part of our Liga MX predictions coverage.

Our famous predictive model currently indicates a 46.6% chance of Club America winning, a 28.2% chance for Guadalajara, and a 25.3% chance of a draw. Additionally, the 2.5-goal over/under has a 50.5% chance of going over., with a 53.7% likelihood that both teams score.

Latest betting odds

We have researched the best Liga MX odds in America for this game, which are listed here:

• Moneyline: Guadalajara +160, Club America +155
• Total Goals: Over/Under 2.5 (-136/+104)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Moneyline: Club America @ +155 via DraftKings
• Total Goals: Under 2.5 @ +104 via FanDuel

According to our Liga MX best bets, the top play to make on this game is Club America to win.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Correct score and BTTS projections

Here are the top three most likely final scores according to our model, with a 1-1 draw being the most probable:

• Club America 1-1 Guadalajara (12% probability)
• Club America 1-0 Guadalajara (10.5%)
• Club America 2-1 Guadalajara (9.3%)

When it comes to the both teams to score (BTTS) market, we project a 53.7% chance of both sides finding the net and a 46.3% chance that at least one doesn’t.

These predictions are based on each team's average score according to our machine learning model, which means the most likely correct score can differ from our predicted winner.

Game info & kickoff details

Saturday's Liga MX action between Club America and Guadalajara at Estadio Banorte is scheduled to commence at 11:15 PM ET.

• Who: Club America vs. Guadalajara
• Date: Saturday, September 19, 2026
• Time: 11:15 PM ET/8:15PM PT
• Venue: Estadio Banorte

Conclusion

According to our computer model, Club America has a 46.6% win probability on Saturday, Guadalajara has a 28.2% win probability, and there is a 25.3% chance that the game will end in a draw.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary Liga MX prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.