Illinois State vs. Southern Illinois: College Football Week 7 Prediction, Picks & Odds

Illinois State vs. Southern Illinois: Detailed Breakdown

Matchup overview: College Football Week 7

• Teams: Illinois State vs. Southern Illinois
• Date: Saturday, October 17, 2026
• Time: 4:00PM ET
• Venue: Saluki Stadium

Current betting odds

• Spread: Illinois State (-7, -113), Southern Illinois (+7, -110)
• Moneyline: Illinois State -280, Southern Illinois +229
• Total (Over/Under): 54.5 points (-110/-110)

Dimers’ win probabilities

• Illinois State: 70.5%
• Southern Illinois: 29.5%

These probabilities come from two machine learning models that assess more than 100 data points for each college football matchup, combining their outputs to project all our major betting markets.

Projected final score

Our predicted final score for this college football matchup is Illinois State 30-24 Southern Illinois.

This prediction draws on each team's scoring trends and player stats, weighed across both of our data models

Our Prediction: Who Wins?

The numbers give the Illinois State a win probability of 70.5%, while the Southern Illinois have a win probability of 29.5%.

Summary

Illinois State faces off against Southern Illinois in college football action at Saluki Stadium on Saturday, October 17, 2026.

Our Illinois State vs. Southern Illinois predictions, built on real-time data and matchup-specific modeling, help guide your decisions. Remember to bet responsibly and within your financial limits.

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For further insights, explore our expert college football predictions and the best college football bets today, while our in-depth analysis includes college football props, college football futures, college football odds, and the latest college football news.