College football picks today: Week 4 Saturday best bets include Iowa vs. Michigan play [9/26/2026]

Iowa vs. Michigan Over 38.5 points (-108)

• Edge: 5.1%
• Probability: 57.1%
• Matchup: Iowa vs. Michigan (3:30PM ET)

Our model has identified value on Over 38.5 points in Iowa vs. Michigan at -108 odds. A 57.1% probability produces an edge of 5.1%, making this the strongest play for today's college football slate.

Oklahoma vs. Georgia Over 44.5 points (-102)

• Edge: 5.1%
• Probability: 55.6%
• Matchup: Oklahoma vs. Georgia (3:30PM ET)

Oklahoma vs. Georgia over 44.5 points carries a 5.1% edge and a probability of 55.6% at -102 odds, according to our model.

Jackson State -20.5 (-107)

• Edge: 4.4%
• Probability: 56.1%
• Matchup: Southern University vs. Jackson State (7:00PM ET)

Jackson State -20.5 vs. Southern University at -107 odds shows a 4.4% edge, supported by a 56.1% probability in simulations.

Robert Morris vs. Buffalo over 45.5 points (-105)

• Edge: 4.4%
• Probability: 55.6%
• Matchup: Robert Morris vs. Buffalo (3:30PM ET)

A 4.4% edge and 55.6% probability make Robert Morris vs. Buffalo over 45.5 points a value play in the Robert Morris vs. Buffalo matchup, per our model.

Cincinnati +6.5 (-112)

• Edge: 3.6%
• Probability: 56.4%
• Matchup: Kansas State vs. Cincinnati (7:00PM ET)

Cincinnati +6.5 at -112 presents a 3.6% edge, with simulations resulting in a probability of 56.4%.

New Hampshire vs. Sacred Heart Over 44.5 points (-111)

• Edge: 3.5%
• Probability: 56.1%
• Matchup: New Hampshire vs. Sacred Heart (12:00PM ET)

Our model finds value on Over 44.5 points in New Hampshire vs. Sacred Heart at -111, supported by an edge of 3.5%.

Georgia -13.5 (-110)

• Edge: 3.2%
• Probability: 55.6%
• Matchup: Oklahoma vs. Georgia (3:30PM ET)

Our model has uncovered value on Georgia -13.5 at -110. A 55.6% probability produces a 3.2% edge, making this a strong play for today's college football action.

Cincinnati ML (+210)

• Edge: 3.2%
• Probability: 35.4%
• Matchup: Kansas State vs. Cincinnati (7:00PM ET)

A 3.2% edge on a 35.4% probability makes Cincinnati to win at +210a solid value play in today's Kansas State vs. Cincinnati matchup.

Columbia ML (-211)

• Edge: 3.1%
• Probability: 71%
• Matchup: Columbia vs. Georgetown (12:30PM ET)

Our model projects value on Columbia to win at -211. A 71% probability produces a 3.1% edge, making Columbia the favorable ML play in today's matchup.

New Haven vs. Merrimack Over 43.5 points (-109)

• Edge: 3.1%
• Probability: 55.2%
• Matchup: Oklahoma vs. Georgia (1:00PM ET)

Rounding out our top 10 bets, New Haven vs. Merrimack Over 43.5 points at -109 shows a 55.2% probability and a 3.1% edge.

NCAAF best bets summary: Saturday, 9/26/2026

As of 1:35AM ET, here are our top college football bets by edge recommended by our model:

List of upcoming college football games to bet on now

• Texas vs. Tennessee (12:00PM ET, Saturday)
• Illinois vs. Ohio State (12:00PM ET, Saturday)
• Wake Forest vs. Louisville (12:00PM ET, Saturday)
• Ball State vs. Kent State (12:00PM ET, Saturday)
• Colorado State vs. UTSA (12:00PM ET, Saturday)
• Virginia Tech vs. Boston College (12:00PM ET, Saturday)
• UNLV vs. Akron (12:00PM ET, Saturday)
• Colorado vs. Baylor (12:00PM ET, Saturday)
• San Diego State vs. Toledo (12:00PM ET, Saturday)
• Sam Houston State vs. Texas Tech (12:00PM ET, Saturday)

College football offer for Week 4

Make the most of the picks in this article—including Over 38.5 points—with the Underdog Fantasy offer below:

Conclusion

Our college football best bets are locked and loaded for September 26, 2026, featuring plays such as over 38.5 points in the Iowa vs. Michigan matchup and over 44.5 points in the Oklahoma vs. Georgia matchup. Powered by advanced simulations, these picks are here to boost your betting game.

Our predictions are rooted in current data to help you make informed decisions. For additional resources and advice, head to our Responsible Gambling hub.

All odds and probabilities in this article are correct and accurate at the time of publication.