College football picks today: Week 3 Saturday best bets include Murray State vs. Oklahoma State play [9/19/2026]
Get college football picks and best bets for Saturday, September 19, 2026.

Today’s college football picks for September 19, 2026 are here, with Murray State vs. Oklahoma State and Buffalo vs. Penn State among the top plays identified by our model across Saturday’s college football play.
Dimers’ predictive analytics engine runs 24/7, searching the latest football odds to unearth top betting edges. The result? Data-backed picks that help Dimers Pro members make smarter decisions.
List of college football picks today [9/19, updated 3:33AM ET]
Below, you’ll find today’s top 10 college football best bets, ranked by edge for Saturday, September 19, 2026.
Murray State +55.5 (+100)
- Edge: 6.8%
- Probability: 56.8%
- Matchup: Murray State vs. Oklahoma State (7:00PM ET)
Our model has identified value on Murray State +55.5 at +100 odds. A 56.8% probability produces an edge of 6.8%, making this the strongest play for today's college football slate.
Buffalo +41 (-109)
- Edge: 6.0%
- Probability: 58.2%
- Matchup: Buffalo vs. Penn State (12:00PM ET)
Buffalo +41 carries a 6.0% edge and a probability of 58.2% at -109 odds, according to our model.
Mercer +40.5 (-108)
- Edge: 5.3%
- Probability: 57.2%
- Matchup: Mercer vs. Georgia Tech (12:00PM ET)
Mercer +40.5 vs. Georgia Tech at -108 odds shows a 5.3% edge, supported by a 57.2% probability in simulations.
Murray State vs. Oklahoma State under 70.5 points (-106)
- Edge: 5.0%
- Probability: 56.5%
- Matchup: Murray State vs. Oklahoma State (7:00PM ET)
A 5.0% edge and 56.5% probability make Murray State vs. Oklahoma State under 70.5 points a value play in the Murray State vs. Oklahoma State matchup, per our model.
Nicholls State +19 (-113)
- Edge: 4.8%
- Probability: 57.9%
- Matchup: Nicholls State vs. Sam Houston State (7:00PM ET)
Nicholls State +19 at -113 presents a 4.8% edge, with simulations resulting in a probability of 57.9%.
Wagner +58.5 (-110)
- Edge: 4.8%
- Probability: 57.2%
- Matchup: Wagner vs. California (3:30PM ET)
Our model finds value on Wagner +58.5 at -110, supported by an edge of 4.8%.
Old Dominion -3 (-104)
- Edge: 4.5%
- Probability: 55.5%
- Matchup: East Carolina vs. Old Dominion (6:00PM ET)
Our model has uncovered value on Old Dominion -3 at -104. A 55.5% probability produces a 4.5% edge, making this a strong play for today's college football action.
Montana +17.5 (-114)
- Edge: 4.5%
- Probability: 57.8%
- Matchup: Montana vs. Oregon State (11:00PM ET)
A 4.5% edge on a 57.8% probability makes Montana +17.5 at -114a solid value play in today's Montana vs. Oregon State matchup.
Southeastern Louisiana vs. Louisiana-MonroeOver 47.5 points (-108)
- Edge: 4.4%
- Probability: 56.3%
- Matchup: Southeastern Louisiana vs. Louisiana-Monroe (4:30PM ET)
Our model projects value on Over 47.5 points at -108. A 56.3% probability produces a 4.4% edge, making the Over the favorable side in today's matchup.
Valparaiso +24.5 (-113)
- Edge: 4.3%
- Probability: 57.3%
- Matchup: East Carolina vs. Old Dominion (1:00PM ET)
Rounding out our top 10 bets, Valparaiso +24.5 at -113 shows a 57.3% probability and a 4.3% edge.
NCAAF best bets summary: Saturday, 9/19/2026
As of 3:33AM ET, here are our top college football bets by edge recommended by our model:
| Matchup | Bet | Odds | Edge | Prob. |
|---|---|---|---|---|
| Murray State vs. Oklahoma State | Murray State +55.5 | +100 @ FanDuel | 6.8% | 56.8% |
| Buffalo vs. Penn State | Buffalo +41 | -109 @ Caesars | 6.0% | 58.2% |
| Mercer vs. Georgia Tech | Mercer +40.5 | -108 @ FanDuel | 5.3% | 57.2% |
| Murray State vs. Oklahoma State | Under 70.5 points | -106 @ FanDuel | 5.0% | 56.5% |
| Nicholls State vs. Sam Houston State | Nicholls State +19 | -113 @ BetRivers | 4.8% | 57.9% |
| Wagner vs. California | Wagner +58.5 | -110 @ DraftKings | 4.8% | 57.2% |
| East Carolina vs. Old Dominion | Old Dominion -3 | -104 @ Caesars | 4.5% | 55.5% |
| Montana vs. Oregon State | Montana +17.5 | -114 @ FanDuel | 4.5% | 57.8% |
| Southeastern Louisiana vs. Louisiana-Monroe | Over 47.5 Points | -108 @ BetRivers | 4.4% | 56.3% |
| Valparaiso vs. Indiana State | Valparaiso +24.5 | -113 @ DraftKings | 4.3% | 57.3% |
List of upcoming college football games to bet on now
- Coastal Carolina vs. Delaware (11:30AM ET, Saturday)
- Georgia vs. Arkansas (12:00PM ET, Saturday)
- North Carolina vs. Clemson (12:00PM ET, Saturday)
- Arizona State vs. Kansas (12:00PM ET, Saturday)
- Kent State vs. Ohio State (12:00PM ET, Saturday)
- Tulane vs. Kansas State (12:00PM ET, Saturday)
- Akron vs. Minnesota (12:00PM ET, Saturday)
- Bowling Green vs. Iowa State (12:00PM ET, Saturday)
- North Texas vs. Texas State (12:00PM ET, Saturday)
- Buffalo vs. Penn State (12:00PM ET, Saturday)
College football offer for Week 3
Make the most of the picks in this article—including Murray State +55.5—with the Underdog Fantasy offer below:
Conclusion
Our college football best bets are locked and loaded for September 19, 2026, featuring plays such as Murray State +55.5 vs. Oklahoma State and Buffalo +41. Powered by advanced simulations, these picks are here to boost your betting game.
Our predictions are based on current data to help you make informed decisions. For additional resources and advice, head to our Responsible Gambling hub.
All odds and probabilities in this article are correct and accurate at the time of publication.



