Los Angeles Chargers vs. Kansas City Chiefs: Experts release early Week 15 predictions [2025]

The Los Angeles Chargers and Kansas City Chiefs will meet in Week 15 of the NFL season at GEHA Field at Arrowhead Stadium on Sunday, December 14, 2025, starting at 1:00PM ET.

Early simulations from Dimers' trusted NFL model favor the Chiefs as the most likely winner of this AFC West rivalry matchup.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Chargers vs. Chiefs predictions page.

LA Chargers vs. Kansas City early predictions

Leveraging trusted machine learning and analysis, we have simulated the Chargers vs. Chiefs game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Chargers 31%, Chiefs 69%
• Predicted final score: Chargers 19-25 Chiefs
• Spread: Chargers (+5.5) 50%, Chiefs (-5.5) 50%
• Total points (44.5): Over 55%, Under 45%

As of December 8, 2025, these Chargers-Chiefs numbers and predictions reflect the latest data and insights available.

Chargers vs. Chiefs Week 15 details

The NFL Week 15 matchup between the Chiefs and Chargers at GEHA Field at Arrowhead Stadium is scheduled for December 14, 2025.

• Who: Los Angeles Chargers vs. Kansas City Chiefs
• Date: Sunday, December 14, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: GEHA Field at Arrowhead Stadium

Chargers vs. Chiefs opening odds

We've researched the best betting odds across America for this Week 15 game, which are listed here:

• Spread: Chargers +5.5 (-110), Chiefs -5.5 (-105)
• Moneyline: Chargers +194, Chiefs -230
• Total: Over/Under 44.5 (-110/-110)

Odds may continue to move—track live changes via our NFL odds page.

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Conclusion

We predict the Chiefs, with a 69% win probability, will likely beat the Chargers in Week 15 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Chargers vs. Chiefs game, with human oversight maintaining high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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