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76ers vs. Celtics prediction: Boston favored to win Game 2 [2026 NBA Playoffs]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Philadelphia 76ers vs Boston Celtics predictions for NBA Playoffs Tuesday.
NBA Playoffs action continues on Tuesday at 7:00 PM ET as the Philadelphia 76ers take on the favored Boston Celtics in Game 2 of their 2026 NBA Playoffs series at TD Garden.
Based on the latest simulation results and today’s injury reports, Dimers' proven NBA model predicts the Celtics as the most likely winner of the 76ers vs. Celtics Game 2 matchup.
This prediction follows the latest NBA Injury Report, which suggests the Celtics lineup will feature stars like Jaylen Brown, Jayson Tatum and Payton Pritchard, while the 76ers will rely on Tyrese Maxey, Paul George and VJ Edgecombe.
This article offers further insights into Tuesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.
Sixers vs. Sixers prediction: Who will win Game 2?
Using trusted machine learning and data, we have simulated the outcome of Tuesday's NBA Playoffs matchup between the 76ers and Celtics, forming part of our NBA predictions coverage.
Our independent predictive model gives the Celtics an 86% chance of beating the 76ers in Game 2 of the series. Our predicted final score has the Celtics winning 114-101.
According to our model, the 76ers (+14) have a 55% chance of covering the spread, while the over/under total of 216.5 points has a 51% chance of going over.
76ers vs. Celtics Game 2 odds
We have sourced the best NBA odds in America for this game, which are listed here:
| Bet Type | 76ers | Celtics |
|---|---|---|
| Spread | +14 (-106) | -14 (-114) |
| Moneyline | +730 | -850 |
| Total | o216.5 (-106) | u216.5 (-110) |
All odds are correct at the time of publication and are subject to change.
76ers vs. Celtics picks and best bet for Game 2
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | 76ers +14 | -106 |
| Moneyline | 76ers | +730 |
| Total | Over 216.5 | -106 |
According to our NBA best bets, the top play to make on this game is 76ers +14 at the spread.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
76ers vs. Celtics Game 2 player props
NBA prop bets are a popular way to wager on Tuesday's Philadelphia vs. Boston matchup without necessarily betting on the outcome. We have crunched the numbers to project how each team's leading players will perform at TD Garden.
Tyrese Maxey is expected to lead the 76ers with 25 points, 4 rebounds and 6 assists, while Jaylen Brown is projected to have 30 points, 8 rebounds and 6 assists for the Celtics.
Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and today's NBA first basket picks.
76ers prediction
Our model's projected player stats for the 76ers are:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Tyrese Maxey | 25 | 4 | 6 | 3 | 46 |
| Paul George | 18 | 6 | 3 | 3 | 35 |
| VJ Edgecombe | 15 | 6 | 4 | 2 | 33 |
| Kelly Oubre | 15 | 6 | 2 | 2 | 29 |
| Quentin Grimes | 10 | 3 | 2 | 1 | 20 |
Celtics prediction
Projected points, rebounds, assists and three-pointers made for the Celtics:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Jaylen Brown | 30 | 8 | 6 | 2 | 54 |
| Jayson Tatum | 26 | 10 | 7 | 3 | 56 |
| P. Pritchard | 16 | 4 | 5 | 2 | 32 |
| Derrick White | 15 | 5 | 6 | 2 | 36 |
| Neemias Queta | 10 | 8 | 2 | 0 | 28 |
Sixers vs. Celtics Game 2 updates and essential details
Tuesday's Game 2 between the Celtics and 76ers in the NBA Playoffs is scheduled to start at 7:00 PM ET.
- Who: Philadelphia 76ers vs. Boston Celtics
- Date: Tuesday, April 21, 2026
- Time: 7:00 PM ET/4:00PM PT
- Venue: TD Garden
- NBA Playoffs bracket: Updated NBA Playoffs bracket and schedule
The NBA Playoffs is an annual elimination tournament held to determine the league's champion.
A total of 16 teams, including the 76ers and Celtics, made the 2026 NBA Playoffs, which consists of four rounds: the First Round, Conference Semifinals, Conference Finals, and NBA Finals.
Each round is played as a best-of-seven series, with the first team to four wins progressing to the next round until a champion is crowned.
Conclusion
We predict the Celtics, with an 86% win probability, will likely beat the 76ers in Tuesday's NBA playoffs matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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