MLB picks today: Thursday's MLB best bets include Rays vs. Yankees play [9/24/2026]

Rays vs. Yankees Over 6.5 runs (-106)

• Edge: 9.2%
• Probability: 60.7%
• Matchup: Rays vs. Yankees (7:05PM ET)

Our model has identified value on Over 6.5 runs in Rays vs. Yankees at 51¢ odds. A 60.7% probability produces an edge of 9.2%, making this the strongest play for today's MLB slate.

Diamondbacks vs. Rockies Over 10.5 runs (+108)

• Edge: 7.7%
• Probability: 55.7%
• Matchup: Diamondbacks vs. Rockies (3:10PM ET)

Diamondbacks vs. Rockies over 10.5 runs carries a 7.7% edge and a probability of 55.7% at 48¢ odds, according to our model.

Reds vs. Braves Over 7.5 runs (-104)

• Edge: 6.5%
• Probability: 57.5%
• Matchup: Reds vs. Braves (7:15PM ET)

Reds vs. Braves Over 7.5 runs at 51¢ odds shows a 6.5% edge, supported by a 57.5% probability in simulations.

Marlins vs. Cubs over 7.5 runs (+102)

• Edge: 5.5%
• Probability: 55%
• Matchup: Marlins vs. Cubs (2:20PM ET)

A 5.5% edge and 55% probability make Marlins vs. Cubs over 7.5 runs a value play in the Marlins vs. Cubs matchup, per our model.

Padres vs. Dodgers Over 7.5 runs (+102)

• Edge: 4.6%
• Probability: 54.1%
• Matchup: Padres vs. Dodgers (10:10PM ET)

Padres vs. Dodgers Over 7.5 runs at 50¢ presents a 4.6% edge, with simulations resulting in a probability of 54.1%.

Guardians vs. Red Sox Over 7.5 runs (+100)

• Edge: 4.4%
• Probability: 54.4%
• Matchup: Guardians vs. Red Sox (6:45PM ET)

Our model finds value on Over 7.5 runs in Guardians vs. Red Sox at +100, supported by an edge of 4.4%.

Mets vs. Rangers Over 8.5 runs (+104)

• Edge: 4.3%
• Probability: 53.3%
• Matchup: Mets vs. Rangers (2:35PM ET)

Our model has uncovered value on Mets vs. Rangers Over 8.5 runs at 49¢. A 53.3% probability produces a 4.3% edge, making this a strong play for today's MLB action.

Brewers vs. Phillies Over 8.5 runs (+104)

• Edge: 3.8%
• Probability: 52.8%
• Matchup: Brewers vs. Phillies (6:05PM ET)

A 3.8% edge on a 52.8% probability makes Over 8.5 runs at 49¢a solid value play in today's Brewers vs. Phillies matchup.

Mets ML (+117)

• Edge: 3.7%
• Probability: 48.7%
• Matchup: Mets vs. Rangers (2:35PM ET)

Our model projects value on Mets to win at 46¢. A 48.7% probability produces a 3.7% edge, making Mets the favorable ML play in today's matchup.

Royals ML (+117)

• Edge: 3.4%
• Probability: 48.2%
• Matchup: White Sox vs. Royals (2:10PM ET)

Rounding out our top 10 bets, Royals to defeat White Sox at 46¢ shows a 48.2% probability and a 3.4% edge.

MLB best bets summary: Thursday, 9/24/2026

As of 3:33AM ET, here are our top MLB bets by edge recommended by our model:

List of upcoming MLB games to bet on [9/24/2026]

• Cardinals vs. Pirates (12:35PM ET, Thursday)
• White Sox vs. Royals (2:10PM ET, Thursday)
• Marlins vs. Cubs (2:20PM ET, Thursday)
• Mets vs. Rangers (2:35PM ET, Thursday)
• D-Backs vs. Rockies (3:10PM ET, Thursday)
• Brewers vs. Phillies (6:05PM ET, Thursday)
• Guardians vs. Red Sox (6:45PM ET, Thursday)
• Rays vs. Yankees (7:05PM ET, Thursday)
• Reds vs. Braves (7:15PM ET, Thursday)
• Angels vs. Mariners (9:40PM ET, Thursday)
• Astros vs. Athletics (9:40PM ET, Thursday)
• Padres vs. Dodgers (10:10PM ET, Thursday)

Conclusion

Our MLB best bets are locked and loaded for September 24, 2026, featuring plays such as over 6.5 runs in the Rays vs. Yankees matchup and over 10.5 runs in the Diamondbacks vs. Rockies matchup. Powered by advanced simulations, these picks are here to boost your betting game.

Our predictions are grounded in current data to help you make informed decisions. For additional resources and advice, head to our Responsible Gambling hub.

All odds and probabilities in this article are correct and accurate at the time of publication.