Wyoming vs. San Jose State prediction favors San Jose State to win in college football Week 6 [2026]

Using trusted machine learning and data analysis, we have re-simulated the result of Wyoming vs. San Jose State, forming part of our college football predictions coverage.

Our independent predictive model currently gives San Jose State a 62.8% chance of defeating Wyoming. Our predicted final score has San Jose State winning 24-19. According to our model, Wyoming (+5) has a 51.5% chance of covering the spread, while the over/under total of 42.5 points has a 54.9% chance of going over.

Latest betting odds

We have sourced the best college football odds in America for this game, which are listed here:

• Spread: Wyoming +5 (-110) / San Jose State -5 (-113)
• Moneyline: Wyoming +163, San Jose State -176
• Total: Over/Under 42.5 (-105/-108)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Wyoming +5 @ -110 via BetRivers
• Moneyline: Wyoming @ +163 via Caesars
• Total: Over 42.5 @ -105 via FanDuel

According to our college football best bets, the top play to make on this game is Over 42.5 total points.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Friday's college football action between San Jose State and Wyoming at CEFCU Stadium is scheduled to start at 9:00 PM ET.

• Who: Wyoming vs. San Jose State
• Date: Friday, October 9, 2026
• Time: 9:00 PM ET/6:00PM PT
• Venue: CEFCU Stadium

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Conclusion

We predict San Jose State, with a 62.8% win probability, will likely beat Wyoming in Friday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.