The 2026 NFL season opens with a conference heavyweight clash: the Buffalo Bills travel to NRG Stadium to face the Houston Texans on Sunday, September 13. Kickoff is still weeks away, but the early markets are already posted, and the quarterback props are where the most interesting Week 1 numbers live.
With Josh Allen and C.J. Stroud trading snaps in a game the market can barely separate, the passing markets are the place to look for value. Bet365 has priced an intriguing passing yards prop around Buffalo's franchise quarterback.
Bet365 is offering odds of +200 on Josh Allen to throw for 250 or more yards against the Texans.
Note: Odds in this article are correct at time of publication and subject to change.
| Player | 200+ Yards | 225+ Yards | 250+ Yards |
|---|---|---|---|
| Josh Allen | -190 | +105 | +200 |
| C.J. Stroud | -260 | -125 | +155 |
| Player | 1+ TD | 2+ TDs | 3+ TDs |
|---|---|---|---|
| Josh Allen | -365 | +160 | +650 |
| C.J. Stroud | -440 | +130 | +600 |
Explore the interactive widget below to discover the latest spread, over/under, and moneyline betting odds and probabilities for the Bills-Texans game at NRG Stadium.
Check out all the important details on the game, as well as the best odds sourced from the top sportsbooks in the country.
The key information you need before the Bills vs. Texans NFL game.
Odds for the key markets in the Bills-Texans matchup.
The odds and lines presented here are the best available from selected sports betting sites at the time of publication and are subject to change.
| Sportsbook | New-user offer |
|---|---|
| Bet365 | Bet $10, Get $365 in bonus bets (no bonus code required) |
Utilizing state-of-the-art data analysis and advanced algorithms, the experts at Dimers have performed 10,000 simulations of the Bills vs. Texans matchup.
According to Dimers' predictive analytics model, the Bills are more likely to win at NRG Stadium. This prediction is based on the model giving the Bills a 54% chance of winning the game, with a projected final score of Bills 24, Texans 22.
The model also leans to the Bills covering the 1.5-point spread, with the projected two-point margin landing just the right side of the number. On the total, the model's projected 46-point combined score sits marginally above Bet365's posted 44.5.
These predictions and probabilities are accurate at the time of publication but are subject to potential changes.
Our top pick for the Bills vs. Texans game is to bet on the Bills -1.5 (+100) at Bet365.
Taking even money on a road favorite in a game the model projects Buffalo to win by two is the cleanest value on the board — the spread and the moneyline are priced almost identically, so the extra half-point of risk comes at effectively no cost. This expert betting advice is based on world-class modeling and valuable betting intelligence, designed to help you make more informed decisions.
Week 1 opens with one of the tightest lines on the slate. Buffalo travels to Houston as a 1.5-point favorite with the moneyline sitting at -115, and Bet365's total of 44.5 signals a book expecting a low-scoring, defensively contested afternoon rather than a shootout.
The headline angle is Josh Allen's passing volume. At +200 to clear 250 yards, he's a value play in a game script that should keep Buffalo throwing late — and if you'd rather back Allen without needing the ceiling outcome, Bet365's +160 price on 2+ passing touchdowns is the more conservative route to the same read on Buffalo's passing attack.

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