Reds vs. Pirates Prediction and Odds - Sep 28, 2022

MLB action continues on Wednesday at 12:35PM ET as the Cincinnati Reds square off with the Pittsburgh Pirates at PNC Park.

Bryse Wilson (3-9, 5.95 ERA) will get the ball for the Pirates, up against Luis Cessa (4-4, 4.78 ERA) for the Reds.

Dimers' free betting picks for Reds vs. Pirates, as well as game predictions and betting odds, are detailed below.

Who will win Reds vs. Pirates?

Based on advanced computer power and data, Dimers.com has simulated Wednesday's Reds-Pirates MLB matchup 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, currently gives the Pirates a 51% chance of defeating the Reds.

More: Reds vs. Pirates Simulated 10,000 Times

Reds vs. Pirates Odds

• Run Line: Pirates +1.5 (-190), Reds -1.5 (+164)
• Moneyline: Pirates -115, Reds +100
• Total: Over/Under 7.5 (-115/+100)

Run Line, Moneyline and Over/Under

The Pirates are listed as +1.5 underdogs against the Reds, with -190 at BetMGM the best odds currently available.

For the favored Reds (-1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at +164.

BetMGM currently has the best moneyline odds for the Pirates at -115. That means you can risk $115 to win $100, for a total payout of $215, if they get the W.

Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for the Reds at +100, where you can risk $100 to win $100, for a total payout of $200, if they come out on top.

The Over/Under for total runs scored sits at 7.5 with FanDuel Sportsbook, which currently has the best odds for the Over at -115, while BetMGM currently has the best odds for the Under at +100.

As always, make sure you check the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Pirates (+1.5) are a 63% chance of covering the run line, while the 7.5-run Over/Under is a 56% chance of going Over.

More: Free Online Bet Tracker

Best Bets for Reds vs. Pirates

• Run Line: Reds -1.5 @ +164 via FanDuel Sportsbook
• Moneyline: Reds @ +100 via DraftKings Sportsbook
• Total: Over 7.5 @ -115 via FanDuel Sportsbook (56% probability)

Dimers' best bets are based on complex modeling and betting expertise to serve you the best possible plays every day of the year.

Even though the Pirates are more likely to cover the run line, our best bet of Reds -1.5 is based on the chance of that happening, according to DimersBOT, and the top odds available.

And while the Pirates are more likely to win the game, according to DimersBOT, betting on the Reds moneyline is the best option due to the edge identified when comparing our data-led probabilities to the sportsbooks' odds currently available.

Taking advantage of the edges published here at Dimers.com is crucial to being profitable in the long run.

Reds vs. Pirates Prediction

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Dimers has full coverage of Wednesday's Reds-Pirates matchup, including pregame predictions, free picks, and live win probabilities.

Remember, DimersBOT updates often, so refresh this article for the latest betting analysis ahead of Reds vs. Pirates on Wednesday September 28, 2022.

Reds vs. Pirates 2022 Game Info

Wednesday's action between the Pirates and Reds at PNC Park is scheduled to commence at 12:35PM ET.

• Who: Cincinnati Reds vs. Pittsburgh Pirates
• Date: Wednesday September 28, 2022
• Time: 12:35PM ET / 9:35AM PT
• Venue: PNC Park

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What other MLB games are on today?

The Reds and Pirates aren't the only two MLB teams you can bet on. DimersBOT never stops and we've got picks and top bets for each and every MLB game via our MLB Predictions page.

Not only do we provide with you quality predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Check it out now!

Lastly, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities matched against the best odds to win the World Series.