Phillies vs. Cubs Prediction and Odds - Sep 28, 2022

The Chicago Cubs take on the Philadelphia Phillies in MLB action at Wrigley Field on Wednesday, commencing at 7:40PM ET.

Hayden Wesneski (2-1, 2.46 ERA) will start for the Cubs, up against Aaron Nola (10-12, 3.28 ERA) for the Phillies.

Dimers' free betting picks for Phillies vs. Cubs, plus game predictions and best odds, are featured in this article.

Who will win Phillies vs. Cubs?

Using trusted computer power and data, Dimers.com has simulated Wednesday's Phillies-Cubs MLB matchup 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, currently gives the Phillies a 62% chance of beating the Cubs.

More: Free Betting Guide for Phillies vs. Cubs

Phillies vs. Cubs Odds

• Run Line: Cubs +1.5 (-105), Phillies -1.5 (-110)
• Moneyline: Cubs +165, Phillies -189
• Total: Over/Under 6.5 (-110/-104)

Run Line, Moneyline and Over/Under

The Cubs are listed as +1.5 underdogs against the Phillies, with -105 at DraftKings Sportsbook the best odds currently available.

For the favored Phillies (-1.5) to cover the run line, Caesars Sportsbook has the best odds currently on offer at -110.

BetMGM currently has the best moneyline odds for the Cubs at +165. That means you can bet $100 to profit $165, earning a total payout of $265, if they win.

Meanwhile, Caesars Sportsbook currently has the best moneyline odds for the Phillies at -189, where you can risk $189 to win $100, for a total payout of $289, if they come out on top.

The Over/Under is set at 6.5 with Caesars Sportsbook, which currently has the best odds for the Over at -110, while FanDuel Sportsbook currently has the best odds for the Under at -104.

As always, make sure you check the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Cubs (+1.5) are a 51% chance of covering the run line, while the Over/Under total of 6.5 runs is a 60% chance of going Over.

More: Track Your Bets via Dimers' Bet Center

Best Bets for Phillies vs. Cubs

• Run Line: Cubs +1.5 @ -105 via DraftKings Sportsbook (51% probability)
• Moneyline: Cubs @ +165 via BetMGM (0.2% edge)
• Total: Over 6.5 @ -110 via Caesars Sportsbook (60% probability) 🔥

Every time you see a 🔥, that means it's one of Dimers' best bets today across all major pro and college sports.

Dimers' best bets are based on world-class modeling and wagering intelligence to help you make more informed decisions with your state's legal sportsbooks.

While the Phillies are more likely to win the game, according to DimersBOT, taking the Cubs moneyline is the best option because of the edge found when comparing our data-led probabilities to the sportsbooks' odds currently available.

Taking advantage of the edges published here at Dimers.com is crucial to being a profitable sports bettor in the long run.

Phillies vs. Cubs Probabilities

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Dimers has full coverage of Wednesday's Phillies-Cubs matchup, including pregame predictions, computer picks, and live updates.

Remember, DimersBOT updates frequently, so keep an eye on this article for any changes to our betting analysis ahead of Phillies vs. Cubs on Wednesday September 28, 2022.

Phillies vs. Cubs 2022 Game Info

Wednesday's action between the Cubs and Phillies at Wrigley Field is scheduled to begin at 7:40PM ET.

• Who: Philadelphia Phillies vs. Chicago Cubs
• Date: Wednesday September 28, 2022
• Time: 7:40PM ET / 4:40PM PT
• Venue: Wrigley Field

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Want more MLB predictions like this?

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We use the power of predictive analytics to find value in the markets so we can write the best MLB betting previews available. We're able to do this by comparing our own probabilities against the sportsbooks' odds (aka Vegas odds) the minute they go live.

So, get ahead of the game and beat the bookies today – it's only a click away.

Finally, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities compared to the best odds to win the World Series.