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Thunder vs. Celtics prediction: Oklahoma City favored to win Wednesday's NBA game [3/25/2026]

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Written by Ryan Leaver

Get Oklahoma City Thunder vs Boston Celtics predictions for NBA Wednesday.

Oklahoma City Thunder-Boston Celtics Predictions and Game Preview.
Oklahoma City Thunder vs. Boston Celtics NBA prediction for Wednesday, March 25, 2026.

NBA action continues on Wednesday at 7:30 PM ET as the Oklahoma City Thunder take on the Boston Celtics at TD Garden.

Based on updated simulation results and today’s injury updates, Dimers' proven NBA model predicts the Thunder as the most likely winner of the Thunder vs. Celtics game.

This prediction follows the latest NBA Injury Report, which suggests the Celtics lineup will feature players like Jaylen Brown, Jayson Tatum and Derrick White, while the Thunder will be led by Shai Gilgeous-Alexander, Chet Holmgren and Jalen Williams.

This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Thunder vs. Celtics prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the result of Wednesday's NBA matchup between the Thunder and Celtics, forming part of our NBA predictions coverage.

Our independent predictive model gives the Thunder a 59% chance of defeating the Celtics. Our predicted final score has the Thunder winning 112-109.

According to our model, the Thunder (-2.5) have a 53% chance of covering the spread, while the over/under total of 222 points has a 51% chance of going over.

 

Thunder vs. Celtics odds

We have sourced the best NBA odds in America for this game, which are listed here:

Bet Type Thunder Celtics
Spread -2.5 (-105) +2.5 (-115)
Moneyline -130 +118
Total o222 (-110) u222 (-110)

All odds are correct at the time of publication and are subject to change.

Thunder vs. Celtics picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Thunder -2.5 -105
Moneyline Thunder -130
Total Over 222 -110

According to our best NBA bets for Wednesday, the top play to make on this game is Thunder -2.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Thunder vs. Celtics player props

Betting on Oklahoma City vs. Boston NBA player props? We have crunched the numbers to project how each team's leading players will perform at TD Garden.

Shai Gilgeous-Alexander is expected to lead the Thunder with 29 points, 4 rebounds and 7 assists, while Jaylen Brown is projected to have 26 points, 7 rebounds and 5 assists for the Celtics.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and today's NBA first basket picks.

Thunder prediction

Our model's projected player stats for the Thunder are:

Player PTS REB AST 3PM DFS
S. Gilgeous-Alexander 29 4 7 2 50
Chet Holmgren 16 8 2 1 35
Jalen Williams 13 4 4 1 26
Ajay Mitchell 12 3 3 1 25
I. Hartenstein 8 7 3 0 25

Celtics prediction

Projected points, rebounds, assists and three-pointers made for the Celtics:

Player PTS REB AST 3PM DFS
Jaylen Brown 26 7 5 2 48
Jayson Tatum 21 8 5 3 44
Derrick White 17 5 5 3 38
P. Pritchard 15 4 5 2 31
Neemias Queta 9 9 2 0 28

Thunder vs. Celtics game-day updates and essential details

Wednesday's matchup between the Celtics and Thunder at TD Garden is scheduled to commence at 7:30 PM ET.

Conclusion

We predict the Thunder, with a 59% win probability, will likely beat the Celtics on Wednesday, with Shai Gilgeous-Alexander projected for a game-high 50 fantasy points.

AI and automation have enhanced this article to quickly deliver accurate Thunder vs. Celtics insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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