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New York City vs. FC Cincinnati prediction, odds, MLS picks [4/22/2026]
Updated: | First published:
Written by Nick Slade, Chief Content Officer
Get New York City vs FC Cincinnati predictions for MLS Wednesday.
NY City will take on Cincinnati in MLS action at Yankee Stadium on Wednesday, beginning at 7:30 PM ET.
Based on the latest simulation results, Dimers' proven MLS model predicts NY City as the most likely winner of the NY City vs. Cincinnati game.
This article offers an expanded analysis of Wednesday's match, including best bets and picks.
New York City vs. FC Cincinnati prediction: Who will win?
Using powerful machine learning and data, we have simulated the result of Wednesday's MLS matchup between NY City and Cincinnati, forming part of our MLS predictions coverage.
Our leading predictive model currently suggests a 58.0% chance of NY City winning, a 21.7% chance for Cincinnati, and a 20.3% chance of a draw.
New York City vs. FC Cincinnati odds
We have researched the best MLS odds in America for this game, which are listed here:
| Market | NY City | Cincinnati | Draw |
|---|---|---|---|
| Moneyline | -115 | +280 | +300 |
All odds are correct at the time of publication and are subject to change.
New York City vs. FC Cincinnati picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Moneyline | NY City | -115 |
According to our MLS best bets, the top play to make on this game is NY City to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
New York City vs. FC Cincinnati: Correct score predictions
Here are the top three most likely final scores according to our model, with a 2-1 NY City win being the most probable:
| Final Score | Probability |
|---|---|
| NYC 2-1 CIN | 9.6% |
| NYC 1-1 CIN | 8.8% |
| NYC 2-0 CIN | 7.5% |
New York City vs. FC Cincinnati game-day updates and essential details
Wednesday's matchup between NY City and Cincinnati in MLS at Yankee Stadium is scheduled to commence at 7:30 PM ET.
- Who: New York City vs. FC Cincinnati
- Date: Wednesday, April 22, 2026
- Time: 7:30 PM ET/4:30PM PT
- Venue: Yankee Stadium
World Cup 2026 watch: James Sands (USA)
NY City defensive midfielder James Sands is firmly on the radar for USMNT supporters at the moment as anticipation grows as we approach the FIFA World Cup 2026, with rising interest in World Cup news and early debates about who will win the World Cup. With the United States set to face Australia, Paraguay, and Türkiye in Group D next year, Sands' club form will be monitored closely.
Conclusion
According to our computer model, NY City has a 58.0% win probability on Wednesday, Cincinnati has a 21.7% win probability, and there is a 20.3% chance that the game will end in a draw.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
Nick Slade, with nearly two decades of experience, is the Chief Content Officer at Cipher Sports Technology Group, overseeing content for Dimers. He specializes in soccer, NBA, and NHL betting, leveraging predictive analytics and machine learning to provide accurate betting insights.
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