Grizzlies vs. Hornets prediction: Why Charlotte is favored to win Saturday's NBA matchup [3/21/2026]

The Charlotte Hornets will take on the Memphis Grizzlies in NBA action at Spectrum Center on Saturday, commencing at 7:00 PM ET.

Based on the latest simulation results and today’s injury news, Dimers' advanced NBA model predicts the Hornets as the most likely winner of the Grizzlies vs. Hornets game.

This prediction follows the latest NBA Injury Report, which suggests the Hornets lineup will feature stars like Brandon Miller, Kon Knueppel and LaMelo Ball, while the Grizzlies will look to GG Jackson, Olivier-Maxence Prosper and Jaylen Wells.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Grizzlies vs. Hornets prediction: Who will win and cover?

Using innovative machine learning and data analysis, we have simulated the result of Saturday's NBA game between the Grizzlies and Hornets 10,000 times as part of our NBA predictions coverage.

Our famous predictive model currently gives the Hornets a 91% chance of defeating the Grizzlies. Our predicted final score has the Hornets winning 124-108.

According to our model, the Grizzlies (+18.5) have a 58% chance of covering the spread, while the over/under total of 232.5 points has a 52% chance of staying under.

Grizzlies vs. Hornets odds

We have sourced the best NBA odds in America for this game, which are listed here:

Bet Type	Grizzlies	Hornets
Spread	+18.5 (-105)	-18.5 (-110)
Moneyline	+1100	-1650
Total	o232.5 (-115)	u232.5 (-105)

All odds are correct at the time of publication and are subject to change.

Grizzlies vs. Hornets picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Spread	Grizzlies +18.5	-105
Moneyline	Grizzlies	+1100
Total	Under 232.5	-105

According to our best NBA bets for Saturday, the top play to make on this game is Grizzlies +18.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

Grizzlies vs. Hornets player props

Looking for Memphis vs. Charlotte NBA prop bets? We use the best information available to project how each team's leading players will perform at Spectrum Center.

GG Jackson is expected to lead the Grizzlies with 15 points, 5 rebounds and 2 assists, while Brandon Miller is projected to have 23 points, 6 rebounds and 4 assists for the Hornets.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and today's NBA first basket picks.

Grizzlies prediction

Our model's projected player stats for the Grizzlies are:

Player	PTS	REB	AST	3PM	DFS
GG Jackson	15	5	2	2	29
O. Prosper	13	4	2	2	25
Jaylen Wells	13	3	2	2	23
Javon Small	11	3	4	2	26
Cam Spencer	11	3	6	2	26

Hornets prediction

Projected points, rebounds, assists and three-pointers made for the Hornets:

Player	PTS	REB	AST	3PM	DFS
Brandon Miller	23	6	4	3	42
Kon Knueppel	21	6	4	3	39
LaMelo Ball	21	5	8	4	45
Miles Bridges	17	6	3	2	33
Coby White	14	3	4	2	27

Grizzlies vs. Hornets game-day updates and essential details

Saturday's matchup between the Hornets and Grizzlies at Spectrum Center is scheduled to commence at 7:00 PM ET.

• Who: Memphis Grizzlies vs. Charlotte Hornets
• Date: Saturday, March 21, 2026
• Time: 7:00 PM ET/4:00PM PT
• Venue: Spectrum Center

Conclusion

We predict the Hornets, with a 91% win probability, will likely beat the Grizzlies on Saturday, with LaMelo Ball projected for a game-high 45 fantasy points.

AI and automation have enhanced this article to quickly deliver accurate Grizzlies vs. Hornets insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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