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Pacers vs. Spurs prediction: San Antonio to win, Victor Wembanyama projected for 28 points in Saturday's NBA game [3/21/2026]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get Indiana Pacers vs San Antonio Spurs predictions for NBA Saturday.
The San Antonio Spurs will take on the Indiana Pacers in NBA action at Frost Bank Center on Saturday, starting at 8:00 PM ET.
Based on updated simulations and today’s injury updates, Dimers' advanced NBA model projects the Spurs as the most likely winner of the Pacers vs. Spurs game.
This prediction follows the latest NBA Injury Report, which suggests the Spurs lineup will feature stars like Victor Wembanyama, De'Aaron Fox and Devin Vassell, while the Pacers will rely on Pascal Siakam, Andrew Nembhard and Jarace Walker.
This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and player prop picks.
Pacers vs. Spurs prediction: Who will win and cover?
Using trusted machine learning and data analysis, we have simulated the result of Saturday's NBA game between the Pacers and Spurs 10,000 times as part of our NBA predictions coverage.
Our famous predictive model currently gives the Spurs an 89% chance of beating the Pacers. Our predicted final score has the Spurs winning 124-109.
According to our model, the Pacers (+17.5) have a 59% chance of covering the spread, while the over/under total of 234.5 points has a 51% chance of staying under.
Pacers vs. Spurs odds
We have sourced the best NBA odds in America for this game, which are listed here:
| Bet Type | Pacers | Spurs |
|---|---|---|
| Spread | +17.5 (-110) | -17.5 (-110) |
| Moneyline | +1100 | -1650 |
| Total | o234.5 (-110) | u234.5 (-106) |
All odds are correct at the time of publication and are subject to change.
Pacers vs. Spurs picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Pacers +17.5 | -110 |
| Moneyline | Pacers | +1100 |
| Total | Under 234.5 | -106 |
According to our best NBA bets for Saturday, the top play to make on this game is Pacers +17.5 at the spread.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Pacers vs. Spurs player props
NBA prop bets are a common way to wager on Saturday's Indiana vs. San Antonio game without necessarily betting on the outcome. We use the best information available to project how each team's leading players will perform at Frost Bank Center.
Pascal Siakam is expected to lead the Pacers with 19 points, 5 rebounds and 3 assists, while Victor Wembanyama is projected to have 28 points, 12 rebounds and 4 assists for the Spurs.
Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and today's NBA first basket picks.
Pacers prediction
Our model's projected player stats for the Pacers are:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Pascal Siakam | 19 | 5 | 3 | 2 | 33 |
| Andrew Nembhard | 15 | 3 | 5 | 2 | 30 |
| Jarace Walker | 14 | 6 | 3 | 2 | 31 |
| Aaron Nesmith | 13 | 4 | 2 | 2 | 24 |
| Jay Huff | 11 | 4 | 2 | 2 | 25 |
Spurs prediction
Projected points, rebounds, assists and three-pointers made for the Spurs:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| V. Wembanyama | 28 | 12 | 4 | 3 | 59 |
| De'Aaron Fox | 20 | 4 | 7 | 2 | 40 |
| Devin Vassell | 15 | 4 | 3 | 2 | 29 |
| Dylan Harper | 13 | 4 | 5 | 1 | 31 |
| Keldon Johnson | 13 | 5 | 1 | 1 | 24 |
Pacers vs. Spurs game-day updates and essential details
Saturday's game between the Spurs and Pacers at Frost Bank Center is scheduled to start at 8:00 PM ET.
- Who: Indiana Pacers vs. San Antonio Spurs
- Date: Saturday, March 21, 2026
- Time: 8:00 PM ET/5:00PM PT
- Venue: Frost Bank Center
Conclusion
We predict the Spurs, with an 89% win probability, will likely beat the Pacers on Saturday, with Victor Wembanyama projected for a game-high 59 fantasy points.
AI and automation have enhanced this article to quickly deliver accurate Pacers vs. Spurs insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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