Guardians vs. Rangers Prediction and Odds - Sep 24, 2022

The Texas Rangers take on the Cleveland Guardians in MLB action at Globe Life Field on Saturday, commencing at 7:05PM ET.

Glenn Otto (6-9, 4.88 ERA) will start for the Rangers, pitting him against Cal Quantrill (13-5, 3.56 ERA) for the Guardians.

Dimers' top betting picks for Guardians vs. Rangers, plus game predictions and best odds, are featured in this article.


Who will win Guardians vs. Rangers?

Using trusted machine learning and data, has simulated Saturday's Guardians-Rangers MLB matchup 10,000 times.

Dimers' renowned predictive analytics model, DimersBOT, currently gives the Guardians a 55% chance of defeating the Rangers.

More: Guardians vs. Rangers Simulated 10K Times

Guardians vs. Rangers Odds

  • Run Line: Rangers +1.5 (-150), Guardians -1.5 (+135)
  • Moneyline: Rangers +120, Guardians -125
  • Total: Over/Under 8 (-105/-105)

Run Line, Moneyline and Over/Under

The Rangers are listed as +1.5 underdogs versus the Guardians, with -150 at DraftKings Sportsbook the best odds currently available.

For the favored Guardians (-1.5) to cover the run line, Caesars Sportsbook has the best odds currently on offer at +135.

DraftKings Sportsbook currently has the best moneyline odds for the Rangers at +120. That means you can bet $100 to profit $120, earning a total payout of $220, if they win.

Meanwhile, Caesars Sportsbook currently has the best moneyline odds for the Guardians at -125, where you can risk $125 to win $100, for a total payout of $225, if they come out on top.

The Over/Under sits at 8 with BetMGM, which currently has the best odds for the Over at -105, while FanDuel Sportsbook currently has the best odds for the Under at -105.

As always, make sure you check all the sportsbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Rangers (+1.5) are a 60% chance of covering the run line, while the 8-run Over/Under is a 54% chance of going Over.

More: Best Free Bet Tracker

Best Bets for Guardians vs. Rangers


Our best bets are based on complex simulations and gambling intelligence to help you make better investments with the legal sportsbooks in your state.

While the Guardians are more likely to win the game, according to DimersBOT, betting on the Rangers moneyline is the best option due to the edge identified when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges published on is one of the keys to achieving long-term profitability as a bettor.

Guardians vs. Rangers Prediction

Click or tap on See Matchup for more.


Dimers has full betting coverage of Saturday's Guardians-Rangers matchup, including pregame predictions, computer picks, and live win probabilities.

Don't forget, DimersBOT updates regularly, so keep checking this page for any changes to our betting insights ahead of Guardians vs. Rangers on Saturday September 24, 2022.


Guardians vs. Rangers 2022 Game Info

Saturday's action between the Rangers and Guardians at Globe Life Field is scheduled to start at 7:05PM ET.

  • Who: Cleveland Guardians vs. Texas Rangers
  • Date: Saturday September 24, 2022
  • Time: 7:05PM ET / 4:05PM PT
  • Venue: Globe Life Field

Looking to join an online sportsbook and start betting on MLB? We've reviewed the best available welcome offers for every legal betting state.

What other MLB games are on today?

The Guardians and Rangers aren't the only two MLB teams you can bet on today. DimersBOT never stops and we've got picks and top bets for every single MLB game in our MLB Bet Hub page.

Not only do we provide with you quality predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Hell yeah it does!

While you're here, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities paired with the best odds on the market.

Related Articles
More Articles