Diamondbacks vs. Dodgers Prediction and Odds - Sep 21, 2022

The Los Angeles Dodgers square off with the Arizona Diamondbacks in MLB action at Dodger Stadium on Wednesday, commencing at 10:10PM ET.

Dustin May (2-2, 3.46 ERA) will start on the mound for the Dodgers, up against Madison Bumgarner (6-15, 5.01 ERA) for the Diamondbacks.

Dimers' free betting picks for Diamondbacks vs. Dodgers, plus game predictions and betting odds, are featured in this article.


Who will win Diamondbacks vs. Dodgers?

Using trusted machine learning and data, Dimers.com has simulated Wednesday's Diamondbacks-Dodgers MLB game 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, gives the Dodgers a 63% chance of getting the W against the Diamondbacks.

More: Free Betting Analysis for Diamondbacks vs. Dodgers

Diamondbacks vs. Dodgers Current Odds

  • Run Line: Dodgers -1.5 (-150), Diamondbacks +1.5 (+140)
  • Moneyline: Dodgers -300, Diamondbacks +270
  • Total: Over/Under 8.5 (-115/+110)

Run Line, Moneyline and Over/Under

The Dodgers are currently -1.5 favorites versus the Diamondbacks, with -150 at FanDuel Sportsbook the best odds currently available.

For the underdog Diamondbacks (+1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at +140.

BetMGM currently has the best moneyline odds for the Dodgers at -300, which means you can risk $300 to win $100, for a total payout of $400, if they get the W.

Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for the Diamondbacks at +270, where you can bet $100 to profit $270, earning a total payout of $370, if they win.

The Over/Under for total runs scored sits at 8.5 with DraftKings Sportsbook, which currently has the best odds for the Over at -115, while Caesars Sportsbook currently has the best odds for the Under at +110.

As always, check out the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Diamondbacks (+1.5) are a 55% chance of covering the run line, while the 8.5-run Over/Under is considered an equal 50-50 chance of hitting.

More: Best Bets Today for All Major Sports

Best Bets for Diamondbacks vs. Dodgers


Any time you see a 🔥, that means you've found one of our best free picks of the day across all sports.

Dimers' best bets are based on detailed simulations and betting intelligence to serve you the best possible plays 24/7.

While the Dodgers are more likely to win the game, according to DimersBOT, betting on the Diamondbacks moneyline is the best option because of the 10.0% edge found when comparing our data-led probabilities to the betting odds currently on offer.

Taking advantage of the edges published on Dimers is crucial to achieving long-term profitability as a bettor.

Diamondbacks vs. Dodgers Prediction

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Dimers has full betting coverage of Wednesday's Diamondbacks-Dodgers matchup, including pregame predictions, free picks, and live updates.

Remember, DimersBOT updates frequently, so keep an eye on this article for the latest betting analysis ahead of Diamondbacks vs. Dodgers on Wednesday September 21, 2022.


Diamondbacks vs. Dodgers 2022 Game Info

Wednesday's matchup between the Dodgers and Diamondbacks at Dodger Stadium is scheduled to start at 10:10PM ET.

  • Who: Arizona Diamondbacks vs. Los Angeles Dodgers
  • Date: Wednesday September 21, 2022
  • Time: 10:10PM ET / 7:10PM PT
  • Venue: Dodger Stadium

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What MLB games are on today?

Now you've got the 411 on Diamondbacks vs. Dodgers, see the latest betting coverage for all upcoming MLB games in Dimers' MLB Bet Hub. There you can find probabilities and odds, plus our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

Lastly, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities compared to the best odds on the market.

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