Cubs vs. Pirates Prediction and Odds - Sep 24, 2022

The Pittsburgh Pirates face the Chicago Cubs in MLB action at PNC Park on Saturday, commencing at 6:35PM ET.

The Pirates will have Johan Oviedo (3-2, 3.69 ERA) start, while the Cubs will counter with Wade Miley (1-1, 3.48 ERA).

Dimers' free betting picks for Cubs vs. Pirates, as well as game predictions and betting odds, are featured in this article.

Who will win Cubs vs. Pirates?

Using high-tech computer power and data, Dimers.com has simulated Saturday's Cubs-Pirates MLB game 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, currently gives the Pirates a 52% chance of beating the Cubs.

More: Full Betting Guide for Cubs vs. Pirates

Cubs vs. Pirates Odds

• Run Line: Pirates +1.5 (-180), Cubs -1.5 (+158)
• Moneyline: Pirates -106, Cubs -110
• Total: Over/Under 7.5 (-110/-106)

Run Line, Moneyline and Over/Under

The Pirates are currently +1.5 underdogs against the Cubs, with -180 at DraftKings Sportsbook the best odds currently available.

For the favored Cubs (-1.5) to cover the run line, Caesars Sportsbook has the best odds currently on the market at +158.

In a sign of how close this game is expected to be, both the Pirates and Cubs are currently at minus-money betting odds on the moneyline.

FanDuel Sportsbook currently has the best moneyline odds for the Pirates at -106. That means you can risk $106 to win $100, for a total payout of $206, if they get the W.

On the other hand, Caesars Sportsbook currently has the best moneyline odds for the Cubs at -110, where you can risk $110 to win $100, for a total payout of $210, if they come out on top.

The Over/Under for total runs scored is set at 7.5 with Caesars Sportsbook, which currently has the best odds for the Over at -110, while FanDuel Sportsbook currently has the best odds for the Under at -106.

As always, make sure you check all of the sportsbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Pirates (+1.5) are a 65% chance of covering the run line, while the 7.5-run Over/Under is a 52% chance of going Over.

More: Free Prop Picks

Best Bets for Cubs vs. Pirates

• Run Line: Pirates +1.5 @ -180 via DraftKings Sportsbook (65% probability)
• Moneyline: Pirates @ -106 via FanDuel Sportsbook (52% probability)
• Total: Over 7.5 @ -110 via Caesars Sportsbook (52% probability)

Our best bets are based on complex modeling and betting expertise to serve you the best possible plays every day of the year.

Cubs vs. Pirates Prediction

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Dimers has full coverage of Saturday's Cubs-Pirates matchup, including pregame predictions, free betting picks, and live scores.

Remember, DimersBOT updates often, so keep an eye on this page for the latest betting insights before Cubs vs. Pirates on Saturday September 24, 2022.

Cubs vs. Pirates 2022 Game Info

Saturday's matchup between the Pirates and Cubs at PNC Park is scheduled to start at 6:35PM ET.

• Who: Chicago Cubs vs. Pittsburgh Pirates
• Date: Saturday September 24, 2022
• Time: 6:35PM ET / 3:35PM PT
• Venue: PNC Park

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What MLB games are on today?

Now you've got the 411 on Cubs vs. Pirates, check out the latest betting coverage for all upcoming MLB games in our MLB Bet Hub. There you can find probabilities and odds, and our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

Lastly, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities compared to the best odds to win the World Series.