Chargers vs. Chiefs Week 2 Prediction and Odds - Sep 15, 2022

NFL Week 2 action continues on Thursday at 8:15PM ET as the Los Angeles Chargers square off with the Kansas City Chiefs at GEHA Field at Arrowhead Stadium.

Dimers' top betting picks for Chargers vs. Chiefs, plus our score prediction, betting odds and projected player stats, are detailed below.

This LA Chargers vs. Kansas City betting preview is brought to you by FanDuel Sportsbook, which has a great No Sweat First Bet promo for new customers.

Who will win Chargers vs. Chiefs?

Using high-tech computer power and data, Dimers.com has simulated Thursday's Chargers-Chiefs NFL game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, currently gives the Chiefs a 66% chance of defeating the Chargers in Week 2 of the NFL season.

More: Chargers vs. Chiefs Simulated 10,000 Times

Chargers vs. Chiefs Game Odds

• Spread: Chiefs -4 (-105), Chargers +4 (-110)
• Moneyline: Chiefs -195, Chargers +175
• Total: Over/Under 53 (-105/-110)

Point Spread, Moneyline and Over/Under

The Chiefs are currently -4 favorites versus the Chargers, with -105 at PointsBet the best odds currently available.

For the underdog Chargers (+4) to cover the spread, Caesars Sportsbook has the best odds currently on the market at -110.

DraftKings Sportsbook currently has the best moneyline odds for the Chiefs at -195, which means you can risk $195 to win $100, for a total payout of $295, if they get the W.

On the other hand, Caesars Sportsbook currently has the best moneyline odds for the Chargers at +175, where you can bet $100 to profit $175, earning a total payout of $275, if they win.

The Over/Under is set at 53 with PointsBet, which currently has the best odds for the Over at -105, as well as the best odds for the Under at -110.

As always, make sure you check all the sportsbooks that are available in your state for the best NFL odds and lines.

According to DimersBOT, the Chiefs (-4) are a 54% chance of covering the spread, while the 53-point Over/Under is a 51% chance of going Under.

More: Track Your Bets via Dimers' Bet Center

Best Bets for Chargers vs. Chiefs

• Spread: Chiefs -4 @ -105 via PointsBet (54% probability)
• Moneyline: Chiefs @ -195 via DraftKings Sportsbook (66% probability)
• Total: Under 53 @ -110 via PointsBet (51% probability)

Dimers' best bets are based on complex modeling and gambling expertise to help you make more informed investments with your state's legal sportsbooks.

Chargers vs. Chiefs Prediction

Dimers.com's predicted final score for LA Chargers vs. Kansas City at GEHA Field at Arrowhead Stadium in Week 2 has the Chiefs winning 28-23.

Click or tap on See Matchup for more.

Dimers has full coverage of this week's Chargers-Chiefs matchup in Week 2, including pregame predictions, best betting picks, and live win probabilities.

Chargers vs. Chiefs Player Props

Who will score the first touchdown in Chargers vs. Chiefs? The data is in.

Featured below are the most likely first touchdown and most likely anytime touchdown scorers for both the Chargers and Chiefs, as well as player stat projections.

And you know what, we provide this information to you for FREE to help you discover the best prop bets for Thursday's game.

According to DimersBOT, Los Angeles' Austin Ekeler is most likely to score the first touchdown in Chargers vs. Chiefs.

DimersBOT gives Ekeler a 12.4% chance of scoring the first TD at GEHA Field at Arrowhead Stadium, while the Chargers RB is a 56.3% chance of scoring an anytime touchdown.

Scroll down for our complete list of first and anytime TD scorer probabilities.

First Touchdown Scorer Probabilities

Los Angeles Chargers

• Austin Ekeler: 12.4% probability
• Mike Williams: 7.5% probability
• Joshua Palmer: 5.8% probability
• Gerald Everett: 5.1% probability
• Justin Herbert: 4.5% probability

Kansas City Chiefs

• Travis Kelce: 10.0% probability
• Clyde Edwards-Helaire: 7.9% probability
• JuJu Smith-Schuster: 7.4% probability
• Marquez Valdes-Scantling: 5.9% probability
• Mecole Hardman: 5.3% probability

Anytime Touchdown Scorer Probabilities

Los Angeles Chargers

• Austin Ekeler: 56.3% probability
• Mike Williams: 38.9% probability
• Joshua Palmer: 31.5% probability
• Gerald Everett: 26.8% probability
• Justin Herbert: 24.4% probability

Kansas City Chiefs

• Travis Kelce: 46.8% probability
• Clyde Edwards-Helaire: 39.5% probability
• JuJu Smith-Schuster: 37.8% probability
• Marquez Valdes-Scantling: 30.2% probability
• Mecole Hardman: 27.8% probability

Chargers-Chiefs Projected Player Stats

Of the starting quarterbacks, the Chargers' Justin Herbert is projected to have a big game with 296 passing yards. The Chiefs' Patrick Mahomes is expected to throw for a whopping 313 yards.

Chargers Starting QB

• Justin Herbert: 296 projected yards

Chiefs Starting QB

• Patrick Mahomes: 313 projected yards

Chargers Rushing

• Austin Ekeler: 61 projected yards
• Justin Herbert: 23 projected yards
• Joshua Kelley: 15 projected yards

Chiefs Rushing

• Clyde Edwards-Helaire: 50 projected yards
• Isiah Pacheco: 26 projected yards
• Patrick Mahomes: 24 projected yards

Chargers Receiving

• Mike Williams: 71 projected yards
• Joshua Palmer: 44 projected yards
• Gerald Everett: 44 projected yards
• DeAndre Carter: 37 projected yards
• Austin Ekeler: 35 projected yards

Chiefs Receiving

• Travis Kelce: 79 projected yards
• JuJu Smith-Schuster: 61 projected yards
• Marquez Valdes-Scantling: 49 projected yards
• Mecole Hardman: 31 projected yards
• Skyy Moore: 21 projected yards

Don't forget, DimersBOT updates often, so keep an eye on this page for the latest betting analysis ahead of Chargers vs. Chiefs on Thursday September 15, 2022.

Chargers vs. Chiefs 2022

The NFL Week 2 game between the Chiefs and Chargers at GEHA Field at Arrowhead Stadium is scheduled to begin at 8:15PM ET.

• Who: Los Angeles Chargers vs. Kansas City Chiefs
• Date: Thursday September 15, 2022
• Time: 8:15PM ET / 5:15PM PT
• Venue: GEHA Field at Arrowhead Stadium

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What other NFL games are on today?

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Want a pick for the Spread? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!