Cardinals vs. Cubs Prediction and Odds - Aug 24, 2022

The Chicago Cubs and St. Louis Cardinals meet in MLB at Wrigley Field on Wednesday, starting at 8:05PM ET.

The Cubs will send Luke Farrell (0-0, 0.00 ERA) to the mound, while the Cardinals are going with Miles Mikolas (10-9, 3.32 ERA).

Dimers' best betting picks for Cardinals vs. Cubs, as well as game predictions and betting odds, are detailed in this article.

Who will win Cardinals vs. Cubs?

Using cutting-edge computer power and data, Dimers.com has simulated Wednesday's Cardinals-Cubs MLB game 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, gives the Cardinals a 65% chance of beating the Cubs.

More: Full Betting Analysis for Cardinals vs. Cubs

Cardinals vs. Cubs Game Odds

• Run Line: Cubs +1.5 (+100), Cardinals -1.5 (-120)
• Moneyline: Cubs +162, Cardinals -179
• Total: Over/Under 8.5 (-105/-105)

Run Line, Moneyline and Over/Under

The Cubs are currently +1.5 underdogs versus the Cardinals, with +100 at BetMGM the best odds currently available.

For the favored Cardinals (-1.5) to cover the run line, BetMGM also has the best odds currently on offer at -120.

FanDuel Sportsbook currently has the best moneyline odds for the Cubs at +162. That means you can bet $100 to profit $162, earning a total payout of $262, if they win.

On the other hand, Caesars Sportsbook currently has the best moneyline odds for the Cardinals at -179, where you can risk $179 to win $100, for a total payout of $279, if they come out on top.

The Over/Under is set at 8.5 with Caesars Sportsbook, which currently has the best odds for the Over at -105, while PointsBet currently has the best odds for the Under at -105.

As always, check out all of the online sportsbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Cardinals (-1.5) are a 52% chance of covering the run line, while the 8.5-run Over/Under is a 55% chance of going Over.

More: Track Your Bets via Bet Center

Best Bets for Cardinals vs. Cubs

• Run Line: Cubs +1.5 @ +100 via BetMGM
• Moneyline: Cardinals @ -179 via Caesars Sportsbook (65% probability)
• Total: Over 8.5 @ -105 via Caesars Sportsbook (55% probability)

Dimers' best bets are based on complex simulations and betting expertise to help you make more informed investments with the legal sportsbooks in the USA.

Even though the Cardinals are more likely to cover the run line, our best bet of Cubs +1.5 is based on the expectation of that happening, according to DimersBOT, and the best odds available.

Cardinals vs. Cubs Prediction

Use our dynamic widget below to see up-to-date Moneyline, Over/Under and Run Line probabilities and odds for St. Louis vs. CHI Cubs, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Wednesday's Cardinals-Cubs matchup, including pregame predictions, free betting picks, and live win probabilities.

Don't forget, DimersBOT updates regularly, so keep checking this page for any changes to our betting analysis before Cardinals vs. Cubs on Wednesday August 24, 2022.

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Cardinals vs. Cubs 2022 Game Info

Wednesday's game between the Cubs and Cardinals at Wrigley Field is scheduled to commence at 8:05PM ET.

• Who: Chicago Cubs vs. St. Louis Cardinals
• Date: Wednesday August 24, 2022
• Time: 8:05PM ET / 5:05PM PT
• Venue: Wrigley Field

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What MLB games are on today?

Now you've got the 411 on Cardinals vs. Cubs, check out the latest betting coverage for all upcoming MLB games in our MLB Bet Hub. There you can find probabilities and odds, and our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

While you're here, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities matched against the best odds available.