Best MLB Betting Picks, Predictions and Parlays: Wednesday September 15, 2021

Last updated: Dec 20, 2023, 12:06PM | Published: Sep 14, 2021, 11:51AM

Baseball gets another day to itself today and we are going in with our Wednesday MLB betting picks.

It's Wednesday September 15, 2021, and, as always, we've simulated all of the day's MLB games 10,000 times each to determine where the value lies for baseball bettors across the United States.

With MLB betting picks, probabilities, odds and predicted scores featured each and every day, check out our top plays for Wednesday's MLB games by reading this article.

Today's MLB best bets and odds are proudly brought to you by Caesars Sportsbook.

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Free MLB Picks For Wednesday September 15, 2021

Marlins vs. Nationals

BET: Nationals at the moneyline with Caesars (+110)

📈 50.2% probability

The Nationals took down the Marlins 8-2 yesterday to level the series at one win apiece and they're looking like the value play again tonight.

At +110 and the more likely team to win, DimersBOT very much likes this play, but you shouldn't goo too crazy with your unit size!

MORE: Marlins vs. Nationals simulator

Reds vs. Pirates

BET: Pirates at the moneyline with Caesars (+135)

📈 2.1% edge on the sportsbooks' odds

Another team that beat today's opponent just yesterday, we're taking the Pirates to cause another upset and beat the Reds tonight.

There's a nice edge here by playing them at the moneyline, but if you're looking for a safer play, the run line looks solid.

MORE: Reds vs. Pirates simulator

D-backs vs. Dodgers

BET: Total runs OVER 9 with Caesars (-110)

📈 55.3% probability

Last up we've got an Over bet for the Arizona - Los Angeles game. It may be a late one for those on the East Coast, but it looks like a high scorer.

Madison Bumgarner is set to pitch for the Diamondback and with an ARE of 4.66, we could see a few runs early from the Dodgers as we towards double figures.

MORE: D-backs vs. Dodgers simulator

Your game not here? Find out who we're betting on for every baseball game on Wednesday via our MLB Bet Hub, where we deliver you MLB predictions and suggested bets.

MLB Parlay For Wednesday, September 15, 2021

🔥 Nationals ML
🔥 Pirates ML
🔥 ARI/LAD o8

Parlay Odds +840

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Ryan Leaver

Senior Sports and Sports Betting Editor

Ryan Leaver has long been entrenched in the world of sports and sports betting, now specializing in the NBA, NFL, college football, college basketball, and soccer. His passion shines through in his detailed game previews, best bets, props, and futures articles for both the NBA and NFL, along with his sharp prop bets for college football and insightful best bets for college basketball. Ryan’s expertise also extends to soccer, where he frequently offers practical betting tips and highlights the bets of the day.

Known for his keen eye for valuable betting promos, Ryan adeptly guides bettors toward opportunities that enhance their wagering experiences. Collaborating often with DimersBOT, his articles are meticulously researched and offer savvy betting advice, making him a trusted source for sports bettors.

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