Western Michigan vs. Buffalo prediction favors Western Michigan to win Week 5 MACtion clash

Using trusted machine learning and data, we have re-simulated the result of Western Michigan vs. Buffalo, forming part of our college football predictions coverage.

Our famous predictive model currently gives Western Michigan an 83.4% chance of defeating Buffalo. Our predicted final score has Western Michigan winning 30-17. According to our model, Western Michigan (-12.5) has a 50.4% chance of covering the spread, while the 46.5-point over/under has a 53.8% chance of going over.

Latest betting odds

We have researched the best college football odds in America for this game, which are listed here:

• Spread: Western Michigan -12.5 (-108) / Buffalo +12.5 (-108)
• Moneyline: Western Michigan -520, Buffalo +480
• Total: Over/Under 46.5 (-105/-110)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Western Michigan -12.5 @ -108 via FanDuel
• Moneyline: Western Michigan @ -520 via FanDuel
• Total: Over 46.5 @ -105 via FanDuel

According to our college football best bets, the top play to make on this game is Over 46.5 total points.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football game between Buffalo and Western Michigan at Broadview Stadium is scheduled to commence at 1:00 PM ET.

• Who: Western Michigan vs. Buffalo
• Date: Saturday, October 3, 2026
• Time: 1:00 PM ET/10:00AM PT
• Venue: Broadview Stadium

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Conclusion

We predict Western Michigan, with an 83.4% win probability, will likely beat Buffalo in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.