Gardner-Webb vs. Charleston Southern prediction: Why Gardner-Webb is favored to win in college football Week 5 [2026]

Using powerful machine learning and data analysis, we have re-simulated the result of Gardner-Webb vs. Charleston Southern, forming part of our college football predictions coverage.

Our independent predictive model currently gives Gardner-Webb a 68.4% chance of defeating Charleston Southern. Our predicted final score has Gardner-Webb winning 27-21. According to our model, Charleston Southern (+7.5) has a 55.6% chance of covering the spread, while the over/under total of 48.5 points has a 51.9% chance of going over.

Latest betting odds

We have sourced the best college football odds in America for this game, which are listed here:

• Spread: Gardner-Webb -7.5 (-113) / Charleston Southern +7.5 (-110)
• Moneyline: Gardner-Webb -306, Charleston Southern +235
• Total: Over/Under 48.5 (-110/-112)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: Charleston Southern +7.5 @ -110 via DraftKings
• Moneyline: Charleston Southern @ +235 via bet365
• Total: Over 48.5 @ -110 via DraftKings

According to our college football best bets, the top play to make on this game is Charleston Southern +7.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football action between Charleston Southern and Gardner-Webb at Buccaneer Field is scheduled to commence at 6:00 PM ET.

• Who: Gardner-Webb vs. Charleston Southern
• Date: Saturday, October 3, 2026
• Time: 6:00 PM ET/3:00PM PT
• Venue: Buccaneer Field

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Make the most of Dimers' Gardner-Webb vs. Charleston Southern predictions by exploring the Bet365 Sportsbook offer below:

Conclusion

We predict Gardner-Webb, with a 68.4% win probability, will likely beat Charleston Southern in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.