Colorado State vs. UTSA prediction favors UTSA to win in college football Week 4 [2026]

Using trusted machine learning and data, we have re-simulated the result of Colorado State vs. UTSA, forming part of our college football predictions coverage.

Our independent predictive model gives UTSA an 85.7% chance of defeating Colorado State. Our predicted final score has UTSA winning 35-21. According to our model, UTSA (-14) has a 51.3% chance of covering the spread, while the over/under total of 57.5 points has a 51.2% chance of staying under.

Latest betting odds

We have researched the best college football odds in America for this game, which are listed here:

• Spread: Colorado State +14 (-108) / UTSA -14 (-110)
• Moneyline: Colorado State +470, UTSA -590
• Total: Over/Under 57.5 (-105/-107)

All odds are correct at the time of publication and are subject to change.

Model picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:

• Spread: UTSA -14 @ -110 via bet365
• Moneyline: UTSA @ -590 via Caesars
• Total: Under 57.5 @ -107 via BetRivers

According to our college football best bets, the top play to make on this game is UTSA to win.

These picks are based on our probabilities matched against the implied probabilities from the current available odds.

Game info & kickoff details

Saturday's college football game between UTSA and Colorado State at Alamodome is scheduled to start at 12:00 PM ET.

• Who: Colorado State vs. UTSA
• Date: Saturday, September 26, 2026
• Time: 12:00 PM ET/9:00AM PT
• Venue: Alamodome

College football Week 4 promos

Make the most of Dimers' Colorado State vs. UTSA predictions by exploring the Bet365 Sportsbook offer below:

Conclusion

We predict UTSA, with an 85.7% win probability, will likely beat Colorado State in Saturday's college football matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

This article's predictions and probabilities are generated by Dimers' proprietary College Football prediction model. Our editorial team reviews the resulting content for accuracy and presentation before publication.