Seattle Seahawks vs. Carolina Panthers: Experts release early Week 17 predictions [2025]

The Seattle Seahawks and Carolina Panthers will meet in Week 17 of the NFL season at Bank of America Stadium on Sunday, December 28, 2025, starting at 1:00 PM ET.

Early simulations from Dimers' trusted NFL model favor the Seahawks as the most likely winner of this NFC showdown.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Seahawks vs. Panthers predictions page.

Seattle vs. Carolina early predictions

Leveraging trusted machine learning and analysis, we have simulated the Seahawks vs. Panthers game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Seahawks 75%, Panthers 25%
• Predicted final score: Seahawks 24-17 Panthers
• Spread: Seahawks (-7.5) 44%, Panthers (+7.5) 56%
• Total points (42.5): Over 50%, Under 50%

As of December 22, 2025, these Seahawks-Panthers figures and predictions reflect the latest data and insights available.

Seahawks vs. Panthers Week 17 details

The NFL Week 17 action between the Panthers and Seahawks at Bank of America Stadium is scheduled for December 28, 2025.

• Who: Seattle Seahawks vs. Carolina Panthers
• Date: Sunday, December 28, 2025
• Time: 1:00 PM ET/10:00AM PT
• Venue: Bank of America Stadium

Seahawks vs. Panthers opening odds

We've researched the best betting odds across America for this Week 17 game, which are listed here:

• Spread: Seahawks -7.5 (-110), Panthers +7.5 (-105)
• Moneyline: Seahawks -425, Panthers +340
• Total: Over/Under 42.5 (-105/-105)

Odds may continue to move—track live changes via our NFL odds page.

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Conclusion

We predict the Seahawks, with a 75% win probability, will likely beat the Panthers in Week 17 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Seahawks vs. Panthers matchup, with human oversight maintaining high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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