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Real Betis vs. Rayo Vallecano prediction, odds, La Liga picks [2/21/2026]

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Written by Damien Souness

Get Real Betis vs Rayo Vallecano predictions for La Liga Saturday.

Real Betis-Rayo Vallecano Predictions and Game Preview.
Real Betis vs. Rayo Vallecano La Liga prediction for Saturday, February 21, 2026.

Real Betis will take on Rayo Vallecano in La Liga action at Estadio de La Cartuja on Saturday, starting at 10:15 AM ET.

Based on updated simulations, Dimers' proven La Liga model projects Real Betis as the most likely winner of the Real Betis vs. Rayo Vallecano game.

This article offers further insights into Saturday's matchup, including best bets and picks.

Real Betis vs. Rayo Vallecano prediction: Who will win?

Using innovative machine learning and data analysis, we have simulated the outcome of Saturday's La Liga match between Real Betis and Rayo Vallecano 10,000 times as part of our La Liga predictions coverage.

Our independent predictive model currently suggests a 52.2% chance of Real Betis winning, a 23.2% chance for Rayo Vallecano, and a 24.6% chance of a draw.

Additionally, the over/under total of 2.5 goals has a 51% chance of staying under, according to our model.

 

Real Betis vs. Rayo Vallecano odds

We have sourced the best La Liga odds in America for this game, which are listed here:

Moneyline

Real Betis Rayo Vallecano Draw
-110 +330 +255

Total Goals

Over 2.5 Under 2.5
-108 -112

All odds are correct at the time of publication and are subject to change.

Real Betis vs. Rayo Vallecano picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Damien Souness
Chief Innovation Officer

Damien Souness leverages over 15 years of experience to create engaging content focused on sports, online gaming and wagering. As Chief Innovation Officer at Cipher Sports Technology Group, the parent company of Dimers, he offers strategic insights and innovative solutions to enhance the player experience.

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