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Trail Blazers vs. Spurs prediction: San Antonio to win, Victor Wembanyama projected for 28 points in Game 2 [2026 NBA Playoffs]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get Portland Trail Blazers vs San Antonio Spurs predictions for NBA Playoffs Tuesday.
NBA Playoffs action continues on Tuesday at 8:00 PM ET as the Portland Trail Blazers look to defy the odds against the San Antonio Spurs in Game 2 of their 2026 NBA Playoffs series at Frost Bank Center.
Based on updated simulation results and today’s injury updates, Dimers' proven NBA model predicts the Spurs as the most likely winner of the Trail Blazers vs. Spurs Game 2 matchup.
This prediction follows the latest NBA Injury Report, which suggests the Spurs lineup will feature players like Victor Wembanyama, Stephon Castle and De'Aaron Fox, while the Trail Blazers will look to Deni Avdija, Jrue Holiday and Toumani Camara.
This article offers a closer look at Tuesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.
Blazers vs. Spurs prediction: Who will win Game 2?
Using trusted machine learning and data, we have simulated the result of Tuesday's NBA Playoffs matchup between the Trail Blazers and Spurs, forming part of our NBA predictions coverage.
Our independent predictive model currently gives the Spurs an 82% chance of beating the Trail Blazers in Game 2 of the series. Our predicted final score has the Spurs winning 115-105.
According to our model, the Trail Blazers (+11.5) have a 53% chance of covering the spread, while the 220.5-point over/under has a 51% chance of going over.
Trail Blazers vs. Spurs Game 2 odds
We have sourced the best NBA odds in America for this game, which are listed here:
| Bet Type | Trail Blazers | Spurs |
|---|---|---|
| Spread | +11.5 (-106) | -11.5 (-105) |
| Moneyline | +500 | -650 |
| Total | o220.5 (-106) | u220.5 (-106) |
All odds are correct at the time of publication and are subject to change.
Trail Blazers vs. Spurs picks and best bet for Game 2
After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Trail Blazers +11.5 | -106 |
| Moneyline | Trail Blazers | +500 |
| Total | Over 220.5 | -106 |
According to our NBA best bets, the top play to make on this game is Trail Blazers to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Trail Blazers vs. Spurs Game 2 player props
NBA player props are a common way to wager on the Portland vs. San Antonio game without necessarily betting on the outcome. We have crunched the numbers to project how each team's leading players will perform at Frost Bank Center.
Deni Avdija is expected to lead the Trail Blazers with 27 points, 8 rebounds and 8 assists, while Victor Wembanyama is projected to have 28 points, 11 rebounds and 3 assists for the Spurs.
Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and today's NBA first basket picks.
Trail Blazers prediction
Our model's projected player stats for the Trail Blazers are:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Deni Avdija | 27 | 8 | 8 | 2 | 53 |
| Jrue Holiday | 17 | 5 | 6 | 2 | 37 |
| Toumani Camara | 12 | 5 | 2 | 2 | 26 |
| Shaedon Sharpe | 12 | 3 | 2 | 1 | 22 |
| Scoot Henderson | 12 | 3 | 3 | 1 | 23 |
Spurs prediction
Projected points, rebounds, assists and three-pointers made for the Spurs:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| V. Wembanyama | 28 | 11 | 3 | 2 | 59 |
| Stephon Castle | 17 | 6 | 8 | 1 | 41 |
| De'Aaron Fox | 17 | 4 | 6 | 2 | 36 |
| Devin Vassell | 14 | 4 | 2 | 2 | 27 |
| Keldon Johnson | 11 | 4 | 1 | 1 | 20 |
Blazers vs. Spurs Game 2 updates and essential details
Tuesday's Game 2 between the Spurs and Trail Blazers in the NBA Playoffs is scheduled to begin at 8:00 PM ET.
- Who: Portland Trail Blazers vs. San Antonio Spurs
- Date: Tuesday, April 21, 2026
- Time: 8:00 PM ET/5:00PM PT
- Venue: Frost Bank Center
- NBA Playoffs bracket: Updated NBA Playoffs bracket and schedule
The NBA Playoffs is an annual postseason tournament held to decide the league's champion.
A total of 16 teams, including the Trail Blazers and Spurs, made the 2026 NBA Playoffs, which spans four rounds: the First Round, Conference Semifinals, Conference Finals, and NBA Finals.
Each round of the NBA Playoffs is played as a best-of-seven series, with the first team to four wins moving on to the next round until a champion is crowned.
Conclusion
We predict the Spurs, with an 82% win probability, will likely beat the Trail Blazers in Tuesday's NBA playoffs matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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