Get NFL anytime TD scorer picks today with projections for every matchup.
Our touchdown scorer predictions for Monday Week 16 are based on the latest data and projections.
Our NFL touchdown predictions for Monday Night Football, Week 16 are live—with Christian McCaffrey and Jonathan Taylor projected as two of the most likely players to score according to the latest Dimers Pro simulation data.
These projections come from Dimers Pro's proprietry model, with our NFL touchdown predictions highlighting which players have the best chance of scoring a touchdown tonight.
In this article, you'll find for Monday Night Football:
Anytime touchdown scorer predictions
First touchdown scorer predictions
TD scorer prop bet with odds of +550
Anytime touchdown scorer predictions for MNF, Week 16, 2025
According to Dimers Pro's proprietary data-driven analysis, McCaffrey leads today's MNF touchdown projections with a 63.4% chance to score, followed by Taylor (63.1%) and George Kittle (40.4%).
Player (Team)
Anytime TD Probability
Christian McCaffrey (49ers)
63.4%
Jonathan Taylor (Colts)
63.1%
George Kittle (49ers)
40.4%
Jauan Jennings (49ers)
36.8%
Tyler Warren (Colts)
26.0%
Michael Pittman (Colts)
23.7%
Josh Downs (Colts)
22.7%
Brian Robinson (49ers)
19.4%
Alec Pierce (Colts)
19.1%
Brock Purdy (49ers)
17.5%
Christian McCaffrey is among the top contenders in the NFL to score a touchdown in Week 16, 2025.
Today’s first touchdown scorer predictions for MNF, Week 16, 2025
For tonight's first touchdown scorer predictions, the Dimers Pro model again highlights Christian McCaffrey with a probability of 17.7%. He is followed closely by Jonathan Taylor at 16.6% and George Kittle at 16.6%. Jauan Jennings (8.1%) and Tyler Warren (5.0%) round out the top five.
For the full set of touchdown projections across every NFL matchup, check out our NFL player projections, where you can sort by anytime TD, first TD, or even 2+ and 3+ touchdowns to find every player’s scoring probabilities.
Best NFL anytime touchdown scorer picks for MNF, Week 16, 2025
After thousands of simulations, incorporating the latest injury news and projected lineups, our model has found the best NFL touchdown scorer bet for MNF tonight.
The best NFL touchdown bet for 49ers vs. Colts is Alec Pierce to score a touchdown at +550 with DraftKings Sportsbook, with our model highlighting an edge of 3.7% for Monday Night Football.
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For Monday Night Football of Week 16, our touchdown scorer predictions are set, with Christian McCaffrey emerging as the most likely anytime TD scorer and also the top candidate to strike first. Still, it’s Alec Pierce who stands out as the best bet, with our model uncovering a 3.7% edge at +550 odds to find the end zone.
These insights are powered by thousands of simulations and the latest lineup and injury data, giving you a sharper edge on NFL touchdown scorer markets. As always, gamble responsibly. If you or someone you know needs support, call 1-800-GAMBLER.
Nick Slade, with nearly two decades of experience, is the Chief Content Officer at Cipher Sports Technology Group, overseeing content for Dimers. He specializes in soccer, NBA, and NHL betting, leveraging predictive analytics and machine learning to provide accurate betting insights.
