Minnesota Vikings vs. New York Giants: Experts release early Week 16 predictions [2025]

The Minnesota Vikings and New York Giants will meet in Week 16 of the NFL season at MetLife Stadium on Sunday, December 21, 2025, starting at 1:00PM ET.

Early simulations from Dimers' trusted NFL model favor the Vikings as the most likely winner of this NFC clash.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Vikings vs. Giants predictions page.

Minnesota vs. NY Giants early predictions

Leveraging trusted machine learning and analysis, we have simulated the Vikings vs. Giants game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Vikings 58%, Giants 42%
• Predicted final score: Vikings 22-20 Giants
• Spread: Vikings (-1.5) 53%, Giants (+1.5) 47%
• Total points (43.5): Over 46%, Under 54%

As of December 15, 2025, these Vikings-Giants numbers and predictions reflect the latest data and insights available.

Vikings vs. Giants Week 16 details

The NFL Week 16 game between the Giants and Vikings at MetLife Stadium is scheduled for December 21, 2025.

• Who: Minnesota Vikings vs. New York Giants
• Date: Sunday, December 21, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: MetLife Stadium

Vikings vs. Giants opening odds

We've researched the best betting odds across America for this Week 16 game, which are listed here:

• Spread: Vikings -1.5 (-105), Giants +1.5 (-115)
• Moneyline: Vikings -118, Giants +104
• Total: Over/Under 43.5 (-110/-110)

Odds may continue to move—track live changes via our NFL odds page.

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Conclusion

We predict the Vikings, with a 58% win probability, will likely beat the Giants in Week 16 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Vikings vs. Giants game, with human oversight maintaining high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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