Detroit Lions vs. Philadelphia Eagles: Experts release early Week 11 predictions [2025]

The Detroit Lions and Philadelphia Eagles will meet in Week 11 of the NFL season at Lincoln Financial Field on Sunday, November 16, 2025, starting at 8:20PM ET.

Initial simulations from Dimers' trusted NFL model favor the Eagles as the most likely winner of this NFC showdown.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Lions vs. Eagles predictions page.

Detroit vs. Philadelphia early predictions

Leveraging trusted machine learning and analysis, we have simulated the Lions vs. Eagles game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Lions 43%, Eagles 57%
• Predicted final score: Lions 23-25 Eagles
• Spread: Lions (+1.5) 50%, Eagles (-1.5) 50%
• Total points (49.5): Over 48%, Under 52%

As of November 10, 2025, these Lions-Eagles numbers and predictions reflect the latest data and insights available.

Lions vs. Eagles Week 11 details

The NFL Week 11 action between the Eagles and Lions at Lincoln Financial Field is scheduled for November 16, 2025.

• Who: Detroit Lions vs. Philadelphia Eagles
• Date: Sunday, November 16, 2025
• Time: 8:20PM ET/5:20PM PT
• Venue: Lincoln Financial Field

Lions vs. Eagles opening odds

We've researched the best betting odds across America for this Week 11 game, which are listed here:

• Spread: Lions +1.5 (-110), Eagles -1.5 (-108)
• Moneyline: Lions +104, Eagles -120
• Total: Over/Under 49.5 (-110/-110)

Odds may continue to move—track live changes via our NFL odds page.

Anytime touchdown scorer predictions

Early NFL player projections for Week 11 highlight the top candidates to score a TD in Lions-Eagles in Week 11:

Detroit Lions

• Jahmyr Gibbs: 65.5% probability
• Amon-Ra St. Brown: 57.7% probability
• David Montgomery: 51.1% probability

Philadelphia Eagles

• Saquon Barkley: 51.4% probability
• Jalen Hurts: 50.1% probability
• A.J. Brown: 42.5% probability

Lions vs Eagles player props

Jahmyr Gibbs is projected to lead rushing for the Lions, while Saquon Barkley is expected to pace the Eagles on the ground.

In the receiving game, our projections favor Detroit's Amon-Ra St. Brown and Philadelphia's A.J. Brown as the likely leaders for each team.

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Conclusion

We predict the Eagles, with a 57% win probability, will likely beat the Lions in Week 11 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Lions vs. Eagles matchup, with human oversight maintaining high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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